断流术后门静脉系统血栓形成的研究

目的研究断流术后门静脉系统血栓形成的临床特征，为其防治提供线索。方法回顾性分析肝硬化门脉高压症行断流术病人194例，研究其门静脉系统血栓形成情况，与PT、KPTT及PLT的关系，再发上消化道出血及生存情况。结果该组门静脉系统血栓发生率为13．92％，血栓组与无血栓组PT、KPTF及PLT水平均无明显差异（P〉0．05），无血栓形成组再出血率明显低于血栓形成组（P〈0．05）。结论断流术后预防门静脉系统血栓形成是降低再出血率的重要一环。抗凝药物应在术后早期（PLT超过正常前）使用。

Study of thrombosis of portal vein after devascularization operation

Objective] To investigate the clinical characteristic of thrombosis of portal vein after devascularization operation,and find out the key for prevention.Methods] Retrospectively analyze 194 patients with liver cirrhosis and portal hypertension who had a devascularization operation.The characteristic of portal vein thrombus,its connection with PT,KPTT and PLT,the recurrent bleeding rate after operation and existing time were studied.Results] The occuring rate of portal vein thrombus after devascularization operation was 13.92%.There were no significent differences of PT,KPTT and PLT between the patients with portal vein thrombus and the one without it(P >0.05).Patients with portal vein thrombus had a higher recurrent bleeding rate than the ones with no portal vein thrombus(P <0.05).Conclusion] The prevention of portal vein thrombus after devascularization operation,was very important to decrease the recurrent bleeding rate after operation.The anti-coagulation therapy should be early administrated after devascularization operation(before the PLT level higher than normal).