微波消解-原子吸收分光光度法测定药品和保健品软胶囊壳中有害元素铬的含量

目的：建立药品和保健品软胶囊壳中有害元素铬的检测方法。方法采用石墨炉-原子吸收分光光度法进行测定，波长357．9 nm ，狭缝宽度为0．7 nm ，氘灯作为背景校正，微波消解对样品进行前处理。结果回归方程：Y＝0．01016 X＋0．00132，在0～50μg · L -1范围内线性关系良好（r＝0．9989），方法的检出限为0．02 mg · kg -1，定量限为0．08 mg · kg -1。高中低3个质量浓度平均回收率分别为101．4％，100．8％和99．7％，RSD分别为1．9％，2．1％和3．2％。结论该方法简便、准确、灵敏度高，适用于药品和保健品软胶囊壳中有害元素铬的含量测定。

Determination of chromium in soft capsules shells of drug and health food by micro-wave digestion-furnace atom absorption spectrometry

Objective To establish a method of microwave digestion-furnace atom absorption spectrometry for the determination of chromium in soft capsule shells of drug and health food .Methods The determination conditions of microwave digestion-furnace at-om absorbance spectrometry were optimized .The content of chromium was determined under the wavelength of 357 .9 nm ,with the slit width 0 .7 nm .Results The calibration curve was linear in the range of 0-50 μg · L -1 （r=0 .998 9） ,the limit of detection was 0 .02 mg · kg -1 ,and the limit of quantification was 0 .08 mg · kg -1 .The average recoveries at three levels were 101 .4% , 100 .8% and 99 .7% ,respectively ,and the RSD were 1 .9% ,2 .1 % and 3 .2% ,respectively .Conclusion This method is simple , accurate ,and suitable for the determination of chromium in soft capsule shells of drug and health food .