MR T2*加权成像和磁敏感加权成像在慢性肝病中的应用现状

肝纤维化是各种慢性肝病的共同特征。在肝纤维化-肝硬化-肝癌进程中，目前认为肝纤维化只有处于特定阶段时经抗纤维化治疗才可以逆转。早期诊断肝纤维化并对其严重程度进行评价，有利于抓住抗纤维化时机及时治疗，有望促进病程逆转。慢性肝病病人肝内存在异常铁沉积，MR T2*加权成像和磁敏感加权成像能检测铁沉积，可评估肝纤维化严重程度及诊断肝硬化和肝癌。就T2*加权成像和磁敏感加权成像在慢性肝病中的研究进展进行综述。

Current status of magnetic resonance T2*weighted imaging and susceptibility weighted imaging in chronic liver disease

Liver fibrosis is a common feature of all kinds of chronic liver disease. During the process from liver fibrosis to cirrhosis and to hepatocellular carcinoma, it is well-known that the liver fibrosis can be reversed after the antifibrotic treatment only in a specific phase. Early diagnosis of liver fibrosis and evaluation of the severity of this disease can be helpful in seizing the appropriate timing for the antifibrotic treatment. Because abnormal iron deposition occurs in liver in patients with chronic liver disease and magnetic resonance T2*-weighted imaging and susceptibility weighted imaging can detect this abnormality, and can be used to assess the severity of liver fibrosis and diagnose liver cirrhosis and hepatocellular carcinoma. In recent years, some progresses in T2*-weighted imaging and susceptibility weighted imaging in chronic liver disease have been made, we aimed to review the progresses in this paper.