结节病概述及误诊原因分析

结节病是一种原因未明的慢性肉芽肿性疾病。其病因和发病机制不明,可能是在某种致病因子的作用下,机体免疫功能低下和局部免疫反应过强的结果。病变可侵犯全身多个器官,以肺和淋巴结发病率为最高。根据病变受累器官的不同,临床表现复杂多样,临床误诊率较高。文章综合国内近20年有关结节病的误诊文献,指出应注意与肺结核,肺癌,淋巴瘤及其他肺间质疾病进行鉴别诊断。

A overview of sarcoidosis: causes for its misdiagnosis

Sarcoidosis is a chronic granulomatous disorder of unknown etiology. The pathogenesis is unknown. A single provoking agent or disordered defense reactions triggered by a variety of insults may be responsible. The lesions occur in multiple body organs, with predominant involvement of lung and lymph nodes. Symptoms depend on the site and degree of involvement and clinical manifestations vary greatly. So misdiagnosis may happen frequently. Having reviewed the literatures on sarcoidosis at home and abroad in the last 20 years, the author of the article indicates that this disorder should be differentiated from pulmonary tuberculosis, lung cancer, lymphoma and other pulmonary interstitial disorders.