| TTV单独及重叠HBV感染的临床研究 |
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| 引用本文： | 吴引伟 刘新钰. TTV单独及重叠HBV感染的临床研究[J]. 中西医结合肝病杂志, 2000, 10(3): 13-14 |
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| 作者姓名： | 吴引伟 刘新钰 |
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| 作者单位： | 吴引伟（南京市第二医院研究室,南京,210003） 刘新钰（南京市第二医院研究室,南京,210003） 姚启燕（南京市第二医院研究室,南京,210003） |
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| 摘 要： | 目的：了解输血传播病毒（Ｔｒａｎｓｆｕｓｉｏｎ Ｔｉａｎｓｍｉｔｔｅｄ Ｖｉｒｕｓ,ＴＴＶ）单独及重叠乙肝病毒（ＨＢＶ）感染的临床特征,探讨其致病性。方法：用套式聚合酶链反应检测血清中ＴＴＶ ＤＮＡ,用ＥＬＩＳＡ法和／或ＰＣＲ法对其他肝炎病毒标志物进行血清学检测。结果：肝病患者ＴＴＶ ＤＮＡ总的阳性率为２１．９％（１０７／４８９）。从临床分型来看,ＴＴＶ单独感染者以急性肝炎（ＡＨ）为多见,占７５％
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| 关 键 词： | TT病毒 重叠感染 聚合酶链反应 病毒性肝炎 |
| 修稿时间： | 2000-03-03 |
Clinical Study on Transfusion Transmitted Virus (TTV)Single Infection and Superinfection with HBV |
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| Wu Yinwei,Liu Xingyu,Yao Qiyan,The Second Hospital of Nanjing City. Clinical Study on Transfusion Transmitted Virus (TTV)Single Infection and Superinfection with HBV[J]. Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases, 2000, 10(3): 13-14 |
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| Authors: | Wu Yinwei Liu Xingyu Yao Qiyan The Second Hospital of Nanjing City |
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| Abstract: | Aim: In order to study the clinical stigma of TTV single infection and superinfection with HBV, and analyze its pathogenesis. Methods: TTV DNA in serum samples was detected by nested Polymerase Chain Reaction (PCR)t the markers of other hepatitis virus in serum were detected by ELISA and/or PCR. Results: TTV DNA was found in 21. 9% (107/489) of patients with liver disease. Acute hepatitis (AH) occured in TTV single infection patients 75% (12/16) more frequently than in superinfection with HBV13% (2/15) (x2 = 11.9, P<0. 01). Chronic hepatitis (CH) occured in superinfection with HBV patients 6 7% (10/15) more frequantly than in TTV single infection patients 19% (3/16) (x2 = 7. 3, P<0. 01). Conclusion: Most of TTV single infection patients displayed as acute hepatitis, the state of illness had no obvious changes when TTV superinfected with HBV. The results suggest that TTV might have pathogenesis. |
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| Keywords: | TT Virus Supcrinfection Polymerase Chain Reaction Virus Hepatitis |
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