硝苯地平控释片联合强力定眩片治疗高血压疗效观察

目的 探讨硝苯地平控释片联合强力定眩片治疗阴虚阳亢型1、2级原发性高血压的临床疗效.方法 将96例阴虚阳亢型1、2级原发性高血压患者随机分成对照组和观察组.对照组给予硝苯地平控释片30 mg,1次/d;观察组给予硝苯地平控释片30 mg,1次/d,强力定眩片6片,3次/d,两组均治疗12周.治疗结束后,测量患者的血压,计算血压疗效以及中医证候疗效.结果 两组治疗后收缩压、舒张压较治疗前均明显降低(P＜0.05),观察组的总有效率85.4％,明显高于对照组的64.6％(P＜0.05)；观察组的证候疗效总有效率为89.5％,明显高于对照组的58.3％ (P＜0.05).结论 硝苯地平控释片联合强力定眩片治疗阴虚阳亢型1、2级原发性高血压,比单独应用硝苯地平控释片更利于血压达标,可更好地控制临床症状.

Clinical observation of Nifedipine Controlled-release Tablets combined with Qiangli Dingxuan Tablets on hypertension

Objective To explore the effect of Nifedipine Controlled-release Tablets combined with Qiangli Dingxuan Tablets on the grades 1 and 2 primary hypertension with the syndrome of Yin deficiency and Yang hyperactivity. Methods Patients (96 cases) with grades 1 and 2 primary hypertension of Yin deficiency and Yang hyperactivity were randomly divided into control group and observation group. The patients in the control group were administered with 30 mg Nifedipine Controlled-release Tablets once daily, and the patients in the observation group were administered with 30 mg Nifedipine Controlled-release Tablets once daily and six pills of Qiangli Dingxuan Tablets three times daily. Both groups were treated for 12 weeks. At the end of the treatment, the blood pressure of patients was measured, and the curative effect of blood pressure and the symptoms curative effect would be calculated. Results After the treatment, systolic pressure and diastolic pressure were obviously descended compared with those before treatment (P < 0.05). The efficiencies of the control and observation groups was 85.4% and 64.6% with significant difference (P < 0.05). Symptoms curative effect in the observation group was 89.5%, which was also obviously higher than 58.3% in the control group (P < 0.05). Conclusion Nifedipine Controlled-release Tablets combined with Qiangli Dingxuan Tablets could control blood pressure on grades 1 and 2 primary hypertension of Yin deficiency and Yang hyperactivity, which is better than Nifedipine Controlled-release Tablets treatment alone.