头颈部癌术后调强放射治疗

目的通过调强放疗对比常规放疗剂量学的优势,表明术后调强放射治疗是今后头颈部癌术后放疗的方向。方法对头颈部癌术后调强放疗的治疗适应证、与手术的间隔时间、靶区定义、患者的固定、CT定位扫描、靶区勾画、逆向放疗计划、靶区和危险器官容积剂量评价(DVH)等分别予以阐述。结果采用术后调强放疗新技术能在肿瘤接受高剂量放射的同时,保护周围正常组织。结论头颈部癌术后调强放疗有比常规放疗更高的肿瘤局部控制率、明显低的口干症等放疗并发症,较好的生存质量。

Postoperative Intensity Modulated Radiotherapy for Head and Neck Cancer

Objective Intensity modulated radiotherapy （IMRT） shows the dosimetric advantage of IMRT over conventional radiotherapy. This study demonstrates that postoperative IMRT is the direction of postoperative radiotherapy on head and neck cancer in the future. Methods General indications, interval between surgery and the start of radiotherapy for postoperative IMRT are presented. The clinical target volumes （CTVs） and planning target volumes （PTVs） are defined. The patients immobilization, treatment-planning CT scans, the delineation and radiation dose of target and critical organs, inverse planning, evaluation for dose-volume histogram （DVHs） of the targets and the organs-at-risk （OARs） are shown. ResuLts IMRT is a highly confurmal radiation new technique enabling delivery of high radiation dose to the tumor while sparing the adjacent normal organs. Conclusions Postoperative IMRT radiation technique for head and neck cancer can potentially improve locoregional control for the advanced-stage patients, reduce side effects and improve quality of live.