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| 云南拉祜族六个基因座的遗传多态性研究 | |
| 引用本文： | 邹苹,申滨,李德林,邹浪萍,褚嘉佑.云南拉祜族六个基因座的遗传多态性研究[J].川北医学院学报,1999,14(2):56-58. |
| 作者姓名： | 邹苹 申滨 李德林 邹浪萍 褚嘉佑 |
| 作者单位： | 1. 昆明市妇幼保健医院,昆明,650031 2. 昆明医学院 3. 云南省高级人民法院司法鉴定科学技术研究所 4. 中国医学科学院生物医学研究所 |
| 基金项目： | 国家自然科学基金资助，CMB 项目资助 |
| 摘 要： | 目的：了解云南拉祜族６ 个短串联重复序列基因座遗传多态性分布。方法：应用复合扩增技术对ＣＳＦ１ＰＯ、ＴＰＯＸ、ＴＨ０１ 、Ｆ１３Ａ０１、ＦＥＳＦＰＳ和ｖＷＡ等６ 个ＳＴＲ基因座进行分析，采用高分辨率的聚丙烯酰胺凝胶电泳分离、银染法显影技术，对云南拉祜族上述６ 个ＳＴＲ基因座进行遗传多态性调查。结果：ＣＳＦ１ＰＯ基因座，观察到８ 个等位基因，２０ 个基因型；ＴＰＯＸ 基因座，观察到５ 个等位基因，１４ 个基因型；ＴＨ０１ 基因座，观察到６ 个等位基因，１７ 个基因型；Ｆ１３Ａ０１ 基因座，观察到６ 个等位基因，１３ 个基因型；ＦＥＳＦＰＳ基因座，观察到７ 个等位基因，１５ 个基因型；ｖＷＡ基因座，观察到７ 个等位基因，１７ 个基因型。结论：上述６ 个短串联重复序列基因座基因频率分布与Ｈａｒｄｙ Ｗｅｉｎｂｅｒｇ 平衡吻合良好。 |
| 关 键 词： | 云南拉祜族 CSF1PO基因座 TPOX基因座 TH01基因座 F13A01基因座 FESFPS基因座 vWA基因座 |
| 文章编号： | 1005-3697(1999)02-0056-03 |
| 修稿时间： | 1999-04-08) |
Distribution of Six STR Loci in Lahu Ethnic Group in China |
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| Zou Ping et al Maternity and Child-care Hospital of Kunning, Kunning,Yunnan.Distribution of Six STR Loci in Lahu Ethnic Group in China[J].Journal of North Sichuan Medical College,1999,14(2):56-58. | |
| Authors: | Zou Ping Maternity and Child-care Hospital of Kunning Kunning Yunnan |
| Institution: | Zou Ping et al Maternity and Child-care Hospital of Kunning, Kunning,Yunnan,650031 |
| Abstract: | Objective This study was aimed for investigating the distribution of six STR loci in LaHu ethnic group. Methods: DNA extraction from blood and multiplex amplification of CSF1PO, TPOX, TH01, F13A01, FESFPS and vWA were carried out. Using denaturingpolyacrylamide gel electrophoresis and silver stain the distribution of allele frequencies of CSF1PO, TPOX, TH01, F13A01, FESFPSand vWA loci in LaHu ethnic group living in Yunnan province was investigated. Results:8 alleles and 20 genotypes of CSF1PO loci, 5 alleles and 14 genotypes of TPOX loci, 6 alleles and 17 genotypes of TH01 loci, 6 alleles and 13 genotypes of F13A01 loci, 7 alleles and 15 genotypes of FESFPS loci, 7 alleles and 17genotypes of vWA loci were observed. Conclusion:The allele distribution of the loci was in good agreement with the Hardy weinberg equibrium. |
| Keywords: | LaHu ethnic group CSF1PO locus TPOX locus TH01 locus F13A01 locus FESFPS locus vWA locusfiliated to Nan Jing medical university Nan jing 210006 Abstract:Objective To investigate the possible relationship between Motilin (MTL) and ga |
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