| 大鼠、小鼠微生物学质量监测中的哨兵动物设置 |
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| 引用本文： | 黄小燕,潘裕,樊海艇,张超超,汤家铭,蔡贞贞.大鼠、小鼠微生物学质量监测中的哨兵动物设置[J].中国比较医学杂志,2014,24(8):67-69. |
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| 作者姓名： | 黄小燕 潘裕 樊海艇 张超超 汤家铭 蔡贞贞 |
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| 作者单位： | 上海中医药大学科技实验中心, 上海 201202;上海中医药大学科技实验中心, 上海 201202;上海中医药大学科技实验中心, 上海 201202;上海中医药大学科技实验中心, 上海 201202;上海中医药大学科技实验中心, 上海 201202;上海中医药大学科技实验中心, 上海 201202 |
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| 基金项目： | 上海中医药大学预算内项目（编号：A1-20140367）。 |
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| 摘 要： | 建立并执行全面的实验动物质量监测，对于确保人员、动物健康和福利，以及实验研究结果的真实性、有效性和可重复性是非常重要的。在实验动物中设置相应的哨兵动物能有效监测实验动物质量。本文对实验动物微生物质量监测中哨兵鼠选择，哨兵鼠与被监测动物接触方式、时间，哨兵鼠放置位置，每笼哨兵鼠代表被监测群体的鼠笼数，以及检测数量、检测频率和项目做一综述。
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| 关 键 词： | 哨兵动物 微生物 微生物学监测 大鼠 小鼠 |
| 收稿时间： | 5/9/2014 12:00:00 AM |
| 修稿时间： | 6/6/2014 12:00:00 AM |
The Microorganisms Monitoring Program in Laboratory Rat And Mouse by Using Sentinel Animals |
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| huangxiaoyan,panyu,fanhaiting,zhangchaochao,tangjiaming and caizhenzhen.The Microorganisms Monitoring Program in Laboratory Rat And Mouse by Using Sentinel Animals[J].Chinese Journal of Comparative Medicine,2014,24(8):67-69. |
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| Authors: | huangxiaoyan panyu fanhaiting zhangchaochao tangjiaming and caizhenzhen |
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| Institution: | Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China |
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| Abstract: | It is very important to establish and execute the all-sided experimental animal quality monitoring in order to guarantee human health, animal health and welfare as well as the authenticity, validity, and repeatability of the experimental research results. Setting corresponding sentinel animals in the experiment can effectively monitor the quality of experimental animals. This article gives a general review of the selection of sentinel rats in the microbiological quality monitoring of the experiment animals, contact form and time between the sentinel rats and the rats being monitored, the placement of sentinel rats, and the number of rat cages being monitored by each cage of sentinel rats, as well as the test quantity, test frequency and the project. |
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| Keywords: | Sentinel animals Microorganisms Microbiological monitoring program Rats Mice |
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