Vasectomy: Study of Circulating Immune-Complexes and its Correlation with Antisperm Immunity in Man, with a Twelve-Month Follow-up Study |
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| Authors: | A LENZI G VALESINI and F DONDERO |
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| Institution: | Laboratory of Immunology of Reproduction and Seminology –V Medical Clinic –and Laboratory of Immunochemistry –I Medical Clinic, University of Rome, La Sapienza", Rome/Italy |
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| Abstract: | Circulating immune-complexes (CIC) have been detected in sera of vasectomized subjects using the Clq Binding Assay. Results seem to indicate that CIC are a feature of the early post-operative period and a consequence of acute immunization against sperm antigens. The progressive disappearance of CIC from the third month after vasectomy with the simultaneous increase in antisperm antibody percentage and titre suggests that CIC could be a temporary feature in vasectomized men and do not lead to a chronic disease, related to a Type III immune reaction. |
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| Keywords: | Vasectomy circulating immune-complexes immunity vasectomy circulating immune-complexes vasectomy antisperm immunity vasectomy |
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