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HBV感染者HBV DNA载量与肝纤维化四项的关系
引用本文:贾海琴,白瑞霞,谭艳,郑小华.HBV感染者HBV DNA载量与肝纤维化四项的关系[J].热带医学杂志,2014(3):345-346,357.
作者姓名:贾海琴  白瑞霞  谭艳  郑小华
作者单位:内蒙古自治区人民医院检验科,内蒙古呼和浩特010017
摘    要:目的研究病毒性乙型肝炎(HBV)的HBV DNA载量与肝纤维化四项的关系。方法收集确诊的病毒性乙型肝炎患者266例,采用荧光定量PCR法检测患者血清样本HBV DNA载量,采用化学发光免疫分析法检测患者血清样本肝纤维化四项。结果 266例HBV感染患者中,HBV DNA阳性率为67%。乙肝病毒载量(血清HBV DNA)与各项肝纤维化指标无明显的相关性,差异均无统计学意义(P0.05)。结论HBV感染患者中,乙肝病毒载量与肝纤维化四项无明显的相关性。

关 键 词:病毒性乙型肝炎  HBV  DNA载量  肝纤维化

The relationship between quantity of hepatitis B virus DNA and hepatic fibrosis in HBV patient
JIA Hai-qin,BAI Rui-xia,TAN Yan,ZHENG Xiao-hua.The relationship between quantity of hepatitis B virus DNA and hepatic fibrosis in HBV patient[J].Journal Of Tropical Medicine,2014(3):345-346,357.
Authors:JIA Hai-qin  BAI Rui-xia  TAN Yan  ZHENG Xiao-hua
Institution:(Department of Clinical Laboratory, Inner Mongolia People's Hospital, Inner Mongolia, Hohhot 010017, China)
Abstract:Objective The relationship between quantity of hepatitis B virus DNA and hepatic fibrosis was studied. Methods 266 HBV patients was collected. And the quantity of hepatitis B was detected by quantity PCR. The hepatic fibrosis was detected by chemiluminescent immunoassay. Results The positive rate of HBV DNA detection was 76% (152/226). There was no relationship in the hepatic fibrosis (P〉0.05). Conclusion There was no relationship between the quantity of hepatitis B virus DNA and hepatic fibrosis in HBV patient.
Keywords:hepatitis B virus  quantity of hepatitis B virus DNA  hepatic fibrosis
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