| 小儿急性淋巴细胞性白血病骨髓中巨核细胞变化 |
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| 引用本文： | 张苏明,宫道华,吴升华,汪敏娟,徐以南,黄如春. 小儿急性淋巴细胞性白血病骨髓中巨核细胞变化[J]. 南京医科大学学报(自然科学版), 1991, 0(1) |
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| 作者姓名： | 张苏明 宫道华 吴升华 汪敏娟 徐以南 黄如春 |
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| 作者单位： | 南京医学院第一附属医院儿科(张苏明，宫道华，吴升华)，南京医学院第一附属医院检验科(汪敏娟，徐以南)，南京医学院第一附属医院检验科(黄如春) |
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| 摘 要： | 报告60例急性淋巴细胞性白血病患儿骨髓中巨核细胞的变化。有18.3%病例的巨核细胞数不减低。说明小儿急性淋巴细胞性白血病巨核细胞数不减低者并非罕见。在巨核细胞数量正常和增高者中,巨核细胞幼稚型比例增高,颗粒型明显增高,产血小板型明显低于正常。大多数病例骨髓片中血小板减少。表明巨核细胞存在成熟障碍。同时发现巨核细胞出现形态学方面改变。
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| 关 键 词： | 巨核细胞 白血病 淋巴母细胞性 儿 |
VARIATIONS OF MEGAKARYOCYTE IN BONE MARROW OF ACUTE LYMPHOCYTIC LEUKEMIA IN CHILDREN |
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| Zhang Suming. VARIATIONS OF MEGAKARYOCYTE IN BONE MARROW OF ACUTE LYMPHOCYTIC LEUKEMIA IN CHILDREN[J]. Acta Universitatis Medicinalis Nanjing, 1991, 0(1) |
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| Authors: | Zhang Suming |
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| Affiliation: | Zhang Suming |
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| Abstract: | Magakaryocytes in bone marrow from 60 children with acute lymphocytic leukaemia(ALL)were studied.Magakaryocyte-count was normal in 18.3% cases,indicating that not all cases ofALL have a reduced megakaryoctic count.Increased immature megakaryocvte,remarkablyincreased granular megakaryocyte,reduced platelet-forming megakaryocyte were found in casesof ALL who had a normal or increased megakaryocyte count.Reduced platelets and changes ofmegakaryocytic morphology were found in majority of the cases of ALL,which suggested ablockage in maturation process of megakaryocytes in cases of ALL. |
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| Keywords: | megakaryocytes leukemia lymphoblastic child |
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