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中国汉族人群Diego血型基因频率调查研究
引用本文:刘宇,牛淼.中国汉族人群Diego血型基因频率调查研究[J].检验医学与临床,2010,7(4):308-309,311.
作者姓名:刘宇  牛淼
作者单位:解放军第二○一医院检验科,辽宁大连,116021
摘    要:目的调查研究中国汉族人群的Diego血型基因频率分布。方法用血型血清学方法对1577例非相关的献血者进行Diego血型的筛选鉴定,并对部分标本进行基因分型和基因测序。结果1577例标本Diego血型血清学鉴定结果,Dia+b-1例,Dia+b+47例,Dia-b+1529例。结论汉族人群DI1基因频率为0.0155,DI2基因频率为0.9845。

关 键 词:汉族  红细胞  基因频率  聚合酶链反应  血型抗原  陕西

Investigation on Diego gene frequency in Chinese Han population
LIU Yu,NIU Miao.Investigation on Diego gene frequency in Chinese Han population[J].Laboratory Medicine and Clinic,2010,7(4):308-309,311.
Authors:LIU Yu  NIU Miao
Institution:LIU Yu,NIU Miao.Department of Clincal Laboratory,210 Hospital of PLA,Dalian,Liaoning 116021,China
Abstract:Objective To investigate the Diego gene frequency in Chinese Han population.Methods 1 577 blood samples from unrelated blood donors were phenotyped for Dia and Dib,part of DNA samples were studied by PCR-SSP and direct sequencing.Results 1 529 of 1577 cases were Di(a-b+),47 of them were Di(a+b+),one of them was Di(a+b-),respectively.Conclusion DI1 gene frequency is 0.015 5,DI2 gene frequency is 0.984 5.
Keywords:han nationality  erythrocytes  gene frequency  polymerase chain reaction  blood group antigens  Shanxi  
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