| 抗敏口服液的毒性及药效学实验研究 |
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| 引用本文： | 肖顺汉,钱永龄.抗敏口服液的毒性及药效学实验研究[J].泸州医学院学报,1992,15(4):249-253. |
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| 作者姓名： | 肖顺汉 钱永龄 |
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| 作者单位： | 泸州医学院药理学教研室，泸州医学院药理学教研室，泸州医学院药理学教研室，泸州医学院药理学教研室，泸州医学院药理学教研室 |
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| 摘 要： |
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| 关 键 词： | 毒性 运行 实验药理学 抗过敏药 |
TOXICOLOGICAL AND PHARMACODYNAMIC EXPERIMENT ON KANG MIN KOU FU-YE |
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| Xiao Shunhan.TOXICOLOGICAL AND PHARMACODYNAMIC EXPERIMENT ON KANG MIN KOU FU-YE[J].Journal of Luzhou Medical College,1992,15(4):249-253. |
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| Authors: | Xiao Shunhan |
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| Institution: | Xiao Shunhan Department of pharmacology |
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| Abstract: | No untoward reaction Was found on mice days after 176g/kg of Kang Min Kou fu-ye (160 tithes of clinical dose) Were administered. 33g/kg/day of this drug Was fed to rats for 90 consecutive days (30 times of clinical dose), no effect Was found on animals'liver function, kideney function, and blood picture; no intoxicational pathological change Was observed in their heart, liver and kidney under light microscope. The Preparation can significantey inhibit not only the guinea pigs' local skin rection and the contraction reaction of rabbits'intestinal smooth muscle caused by histamine, but also the skin reaction of guinea pig caused by PCA and DNCB. The preparation can resist allergic shock caused by egg white. Its antihistamine effect is more rapid, strong, but the time is shorter than that of Astemizole. |
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| Keywords: | Kang Ming Kou fu-ye Virulence pharmacodynamics Animal Laboratory ComPosite (the traditional Chiese Medicine) |
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