雀鹿蕊化学成分研究

目的 研究产自内蒙古自治区的雀鹿蕊的化学成分.方法 雀鹿蕊乙醇提取液依次用石油醚、乙酸乙酯和正丁醇萃取,萃取物经色谱柱重结晶HPLC纯化,数据分析鉴定结构.结果 分离鉴定了13个化合物,(+)-松萝酸(1),2,4-二羟基-6-戊基苯甲酸-3-羟基-4-甲氧羰基-5-戊基苯基酯(2),黑茶渍素(3),2,4-二羟基-3,6-二甲基苯甲酸-3-羟基-4-甲氧羰基-2,5-二甲基苯基酯(4),赤星衣酸乙酯(5),丁二酸(6),十四酸乙酯(7),α-香树脂醇乙酸酯(8),2,4-二羟基-3,6-二甲基苯甲酸甲酯(9),2,4-二羟基-3-醛基-6-甲基苯甲酸甲酯(10),2-羟基-4-甲氧基-6-正戊基苯甲酸(11),2-羟基-4-甲氧基-6-正戊基苯甲酸甲酯(12),2-羟基-4-甲氧基-6-正戊基苯甲酸乙酯(13).结论 化合物2、4、6、7、8、10、12、13为首次从该植物中分离得到.

Chemical constituents of Cladoniae stellardis(Opiz.)

AIM To study the chemical constituents of Cladoniae stellardis(Opiz.) collected from the Inner Mongolia Autonomous Region.METHODS Having obtained the ethanolic extract of Cladoniae stellardis(Opiz.) with petro-ether,ethyl acetate and n-butanol,gel column,recrystallization and HPLC analysis were subjected to purify the extracts and their structure was determined.RESULTS Thirteen compounds were isolated and identified as usuic acid(1),3-hydroxy-4-(methoxycarbonyl)-5-pentylphenyl 2,4-dihydroxy-6-pentylbenzoate(2),atranorin(3),3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 2,4-dihydroxy-3,6-dimethylbenzoate(4),uthyl haematommate(5),succinic acid(6),ethyl myristate(7),α-amyrin acetate(8),methyl 2,4-dihydroxy-3,6-dimethyl benzoate(9),methyl 3-formyl-2,4-dihydroxy-6-methyl benzoate(10),2-hydroxy-4-methoxy-6-n-pentylbenzoic acid(11),methyl 2-hydroxy-4-methoxy-6-pentylbenzoate(12),ethyl 2-hydroxy-4-ethoxy-6-pentylbenzoate(13).CONCLUSION Compounds 2,4,6,7,8,10,12,and 13 are isolated from this plant for the first time.