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| AIDS与肝病患者胃镜活检组织幽门螺杆菌感染和消化性溃疡发现率的临床比较研究 | |
| 引用本文： | 程计林,黄绍萍,须亚红,陆基华,殷科珊,唐荣,徐烈,马学东,苏峥,樊贞瑜,张仁芳,卢洪洲,陈良,冯艳玲.AIDS与肝病患者胃镜活检组织幽门螺杆菌感染和消化性溃疡发现率的临床比较研究[J].胃肠病学和肝病学杂志,2011,20(9):847-849. |
| 作者姓名： | 程计林 黄绍萍 须亚红 陆基华 殷科珊 唐荣 徐烈 马学东 苏峥 樊贞瑜 张仁芳 卢洪洲 陈良 冯艳玲 |
| 作者单位： | 1. 上海市复旦大学附属公共卫生临床中心消化科,上海,201508 2. 上海市复旦大学附属公共卫生临床中心感染科,上海,201508 3. 上海市复旦大学附属公共卫生临床中心肝炎科,上海,201508 4. 上海市复旦大学附属公共卫生临床中心病理科,上海,201508 |
| 摘 要： | 目的探讨艾滋病、肝病和普通人群上中腹不适的患者胃幽门螺旋杆菌（H.pylori）感染发生率的异同,以发现H.pylori感染在诱发艾滋病患者和肝病患者消化性溃疡过程中作用的异同。方法艾滋病组患者46例,肝病组患者668例,非艾滋病非肝病普通人群对照组226例,均有上腹不适,行胃镜检查,活检组织分别进行快速尿素酶和Warthin-Starry银染检测H.pylori感染,同时记录内镜下发现的病变。结果肝病患者H.pylori感染率（36.08%）低于艾滋病患者（43.48%）和普通人群对照组（59.73%）（P〈0.05）,艾滋病患者H.pylori感染低于普通人群对照组患者（P〈0.05）;肝病伴发消化性溃疡患者的H.pylori感染率（45.22%）低于普通人群消化性溃疡患者的H.pylori感染率（80.49%）（P〈0.05）,艾滋病伴发消化性溃疡的H.pylori感染率（50.00%）与普通人群无差异（P〉0.05）。结论 H.pylori肝病患者消化性溃疡的发生与H.pylori感染的关系,不像普通人群消化性溃疡的发生与H.pylori感染的关系密切;而艾滋病患者中H.pylori感染率即使低于普通人群,H.pylori感染仍是促进艾滋病患者发生消化性溃疡的重要因素。 |
| 关 键 词： | 艾滋病 肝病 幽门螺杆菌 消化性溃疡 |
Relationship of AIDS with Helicobacter pylori in gastric mucous epithelium of hepatic disease and peptic ulcer of gastroscopy patients |
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| CHENG Jilin,HUANG Shaoping,XU Yahong,LU Jihua,YIN Keshan,TANG Rong,XU Lie,MA Xuedong,SU Zheng,FAN Zhenyu,ZHANG Renfang,LU Hongzhou,CHEN Liang,FENG Yanling.Relationship of AIDS with Helicobacter pylori in gastric mucous epithelium of hepatic disease and peptic ulcer of gastroscopy patients[J].Chinese Journal of Gastroenterology and Hepatology,2011,20(9):847-849. | |
| Authors: | CHENG Jilin HUANG Shaoping XU Yahong LU Jihua YIN Keshan TANG Rong XU Lie MA Xuedong SU Zheng FAN Zhenyu ZHANG Renfang LU Hongzhou CHEN Liang FENG Yanling |
| Institution: | CHENG Jilin1,HUANG Shaoping1,XU Yahong1,LU Jihua1,YIN Keshan1,TANG Rong1,XU Lie1,MA Xuedong1,SU Zheng1,FAN Zhenyu1,ZHANG Renfang2,LU Hongzhou2,CHEN Liang3,FENG Yanling4 1.Department of Gastroenterology,2.Department of Infectious Diseases,3.Department of Hepatology,4.Department of Pathology,Shanghai Public Health Clinic Center Affiliated to Fudan University,Shanghai 201508,China |
| Abstract: | Objective To understand the difference of helicobacter pylori infection rates among the patients with AIDS,patients with hepatic diseases,and the persons with epigastrium discomfort but without AIDS and hepatic disease,study the role of helicobacter pylori in the pathogenesis of peptic ulcer found in patients with AIDS and patients with hepatic disease.Methods Forty-six patients with AIDS,668 patients with hepatic disease and 226 persons without AIDS and hepatic disease from outpatient service in Shanghai P... |
| Keywords: | AIDS Hepatic disease Helicobacter pylori Peptic ulcer |
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