| 非糜烂性反流病患者食管动力特征分析 |
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| 引用本文： | 何素玉,陈拥军,徐建玉,唐毅,姚勇,孙怡,丁晓梅.非糜烂性反流病患者食管动力特征分析[J].胃肠病学,2011,16(8):487-489. |
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| 作者姓名： | 何素玉 陈拥军 徐建玉 唐毅 姚勇 孙怡 丁晓梅 |
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| 作者单位： | 四川省遂宁市中心医院消化内科(629000) |
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| 摘 要： | 背景：食管动力障碍在胃食管反流病（GERD）的发生中起重要作用。目的：探讨不同类型非糜烂性反流病（NERD）的食管动力特征。方法：选取161例具有典型胃食管反流症状者和20名健康体检者,分别行上消化道内镜检查、24 h食管pH监测和食管测压。纳入内镜检查未见Barrett食管和食管黏膜破损、症状指数≥50%的NERD患者,根据其是否存在病理性酸反流分为异常酸反流组和食管酸高敏组,比较反流组（28例）、高敏组（13例）和对照组（15例）的食管测压结果。结果：反流组下食管括约肌（LES）长度较对照组显著缩短（P〈0.05）,LES压力显著降低（P〈0.05）,高敏组与对照组间则无明显差异。反流组和高敏组食管体部动力障碍均以食管远段为主,表现为收缩波幅降低、蠕动波传导速度减慢和非传导性收缩波比例增加,反流组改变更为明显。结论：不同类型NERD的食管动力特征存在差异。异常酸反流亚型NERD患者存在LES长度和压力异常,食管远段动力障碍更为明显。
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| 关 键 词： | 非糜烂性反流病 食管括约肌 下段 食管动力障碍 食管pH监测 测压法 |
Analysis of Esophageal Motility in Patients with Nonerosive Reflux Disease |
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| HE Suyu,CHEN Yongjun,XU Jianyu,TANG Yi,YAO Yong,SUN Yi,DING Xiaomei.Analysis of Esophageal Motility in Patients with Nonerosive Reflux Disease[J].Chinese Journal of Gastroenterology,2011,16(8):487-489. |
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| Authors: | HE Suyu CHEN Yongjun XU Jianyu TANG Yi YAO Yong SUN Yi DING Xiaomei |
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| Institution: | HE Suyu,CHEN Yongjun,XU Jianyu,TANG Yi,YAO Yong,SUN Yi,DING Xiaomei.Department of Gastroenterology,Suining Central Hospital,Suining,Sichuan Province(629000) |
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| Abstract: | Background:Esophageal motility disorder plays an important role in the pathogenesis of gastroesophageal reflux disease(GERD).Aims:To investigate the characteristics of esophageal motility in different nonerosive reflux disease (NERD) subgroups.Methods:One hundred and sixty-one patients with typical gastroesophageal reflux symptoms and twenty healthy subjects were enrolled.Each individual was evaluated with upper gastrointestinal endoscopy,24-hour esophageal pH monitoring and esophageal manometry.NERD was di... |
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| Keywords: | Nonerosive Reflux Disease Esophageal Sphincter Lower Esophageal Motility Disorder Esophageal pH Monitoring Manometry |
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