| 胆囊切除与结直肠息肉相关性的研究 |
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| 引用本文： | 庄剑辉,李晓波,王美鸿,张哲焱,季晓微,金鑫,钱缙.胆囊切除与结直肠息肉相关性的研究[J].胃肠病学,2011,16(8):482-484. |
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| 作者姓名： | 庄剑辉 李晓波 王美鸿 张哲焱 季晓微 金鑫 钱缙 |
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| 作者单位： | 上海交通大学医学院附属仁济医院消化内科(200127) |
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| 基金项目： | 上海市大学生科技创新性计划 |
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| 摘 要： | 背景：胆囊切除已被认为是结直肠癌的危险因素之一,但胆囊切除与结直肠息肉的关系一直未受到重视。目的：探讨胆囊切除与结直肠息肉的相关性。方法：连续收集经结肠镜排除恶性肿瘤、炎症性肠病、家族性腺瘤性息肉病等疾病的患者425例,根据既往有无胆囊切除史分为胆囊切除组（n=63）和对照组（n=362）,对两组患者结直肠息肉的发生率、内镜下息肉表现和组织学类型进行分析。结果：胆囊切除组结直肠息肉发生率高于对照组（46.0%对37.8%）,但差异无统计学意义（P=0.219）。两组患者息肉的部位和形态均无明显差异（P=0.753,P=0.127）;但胆囊切除患者腺瘤性息肉的发生危险显著高于对照组（OR=1.79,P=0.006）。亚组分析示胆囊切除史≥10年的结直肠息肉发生率与胆囊切除史〈10年无明显差异（P=0.11）。结论：胆囊切除并未增加结直肠息肉发生的危险性,但腺瘤性息肉的发生率显著增高,因此对胆囊切除患者应重视早期结直肠癌和腺瘤性息肉的筛查。
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| 关 键 词： | 胆囊切除术 结肠息肉 结直肠肿瘤 腺瘤性息肉 |
Correlation between Cholecystectomy and Colorectal Polyps |
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| ZHUANG Jianhui,LI Xiaobo,WANG Meihong,ZHA NG Zheyan,JI Xiaowei,JIN Xin,QIAN Jin.Correlation between Cholecystectomy and Colorectal Polyps[J].Chinese Journal of Gastroenterology,2011,16(8):482-484. |
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| Authors: | ZHUANG Jianhui LI Xiaobo WANG Meihong ZHA NG Zheyan JI Xiaowei JIN Xin QIAN Jin |
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| Institution: | ZHUANG Jianhui,LI Xiaobo,WANG Meihong,ZHANG Zheyan,JI Xiaowei,JIN Xin,QIAN Jin.Department of Gastroenterology,Renji Hospital,Shanghai Jiaotong University School of Medicine,Shanghai(200127) |
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| Abstract: | Background:Cholecystectomy has been proved to be one of the risk factors of colorectal cancer,but few attentions have been paid on the association between cholecystectomy and colorectal polyps.Aims:To explore the correlation between cholecystectomy and colorectal polyps.Methods:A total of 425 consecutive patients in whom cancer, inflammatory bowel disease and familial adenomatous polyposis were excluded by colonoscopy were enrolled.Patients were divided into cholecystectomy group(n=63) and control group(n=3... |
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| Keywords: | Cholecystectomy Colonic Polyps Colorectal Neoplasms Adenomatous Polyps |
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