Prophylactic platelet transfusion in children with thrombocytopenic disorders: a retrospective review |
| |
Authors: | Ferrara M Capozzi L Coppola A Save G Coppola L |
| |
Institution: | Department of Pediatrics, The 2nd University of Naples, Naples, Italy. |
| |
Abstract: | The safety of low platelet thresholds for prophylactic transfusions was retrospectively evaluated in 673 children with various thrombocytopenic disorders. In patients with idiopathic thrombocytopenic purpura and X linked thrombocytopenia the threshold for the use of platelet transfusion was based on bleeding events rather than platelet count. In children with hypoproliferative thrombocytopenia and Wiskott-Aldrich syndrome, prophylactic platelet transfusions were used when the platelet count was 10,000/microl in cases of bleeding or infections. The restrictive policy of platelet transfusions was shown to be proved safe in many thrombocytopenic disorders. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|