床旁脑钠肽测定在心力衰竭诊断中的价值研究

目的探讨免疫荧光标记的方法测定脑钠肽对心力衰竭诊断的临床应用价值。方法设心衰组97例及对照组50例,利用荧光免疫法测定血浆脑钠肽,并进行心功能分级及标准化心衰评分,对心衰组与对照组、心衰组治疗前后实验数据,进行统计学处理比较分析。结果心衰组血浆脑钠肽为(874.3±853.5)ng/L;非心衰组脑钠肽(20.4±8.7)ng/L,非心衰组明显低于心衰组(P<0.01)。心衰患者经过抗心衰治疗后,血浆脑钠肽浓度下降至(328.8±336.2)ng/L,P<0.01,具统计学意义。治疗后NYHA心功能分级及标准化心衰评分均显著降低,P<0.01,具统计学差异。结论快速床旁检测脑钠肽测定在心衰诊断、心衰严重程度判断、治疗效果及预后判断中具有较高的应用价值,值得推广。

Investigation of clinical value of plasma brainnatriuretic peptide in the diagnosis of cardiac heart failure.

Objective To investigate the clinical value of plasma brain natriuretic peptide(BNP)by immunofluorescence assay in the diagnosis of cardiac heart failure(CHF).Methods There were two groups,including the control(50) and the trial(97).The plasma BNP concentration was measured with immunofluorescence assay. Then the standardized grades of CHF and the cardiac function class of NYHA were assessed. The statistic methods were employed to analyze the experimental data, such as comparing the data between the control...