Effet de l'entraînement sur l'anabolisme musculaire : analyse de la réceptivité à la testostérone

This study analysed consequences of testosteronemia changes on anabolic process after endurance physical training. During 8 weeks, rats were physically trained in endurance tests. Plasmatic testosterone concentrations were significantly decreased (P < 0.05), weight of three skeletal muscles (soleus, EDL, tibialis anterior) and total muscular protein concentrations were significantly increased (P < 0.05). After endurance physical training muscular hypertrophy was well evidenced (P < 0.05). The analyse of testosterone muscular receptor was performed, permitting two essentials conclusions: according to fibre histological profiles, hormonal receptivity was more profound on fast-twitch muscles (P < 0.05); this hormonal receptivity persists as well as testosteronemia, which was significantly diminished with endurance training.