Nephrolithiasis after bariatric surgery: A comparison of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy |
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Affiliation: | 1. Minimally Invasive Bariatric Surgery and Advanced Laparoscopy Fellowship, Department of Medical Education, Gundersen Medical Foundation, La Crosse, WI, USA;2. Department of Medical Research, Gundersen Medical Foundation, La Crosse, WI, USA;3. Department of General Surgery, Gundersen Health System, La Crosse, WI, USA;4. Department of Urology, Gundersen Health System, La Crosse, WI, USA;1. Division of Nephrology and Hypertension, Fletcher Allen Health Care, Burlington, Vermont;2. Department of Medicine, Baystate Medical Center, Springfield, Massachusetts and Tufts University School of Medicine, Boston, Massachusetts;3. Department of Pediatrics, Baystate Medical Center, Springfield, Massachusetts and Tufts University School of Medicine, Boston, Massachusetts;4. Department of Surgery, Baystate Medical Center, Springfield, Massachusetts and Tufts University School of Medicine, Boston, Massachusetts;5. Division of Endocrinology, Baystate Medical Center, Springfield, Massachusetts and Tufts University School of Medicine, Boston, Massachusetts;6. Renal Division, Baystate Medical Center, Springfield, Massachusetts and Tufts University School of Medicine, Boston, Massachusetts;1. Division of Nephrology, Geisinger Health System, Danville, Pennsylvania, USA;2. Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland, USA;3. Obesity Institute, Geisinger Health System, Danville, Pennsylvania, USA;4. Biomedical & Translational Informatics, Geisinger Health System, Danville, Pennsylvania, USA;5. Division of Nephrology, Loyola University Medical Center, Chicago, Illinois, USA;6. Division of General Internal Medicine, Johns Hopkins University, Baltimore, Maryland, USA;7. Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;1. Divisions of Pediatric Urology and Pediatric Nephrology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio;3. Surgical Weight Loss Center for Teens, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio |
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Abstract: | IntroductionLaparoscopic Roux-en-Y gastric bypass (LRYGB) is known to increase risk for calcium oxalate nephrolithiasis due to hyperoxaluria; however, nephrolithiasis rates after laparoscopic sleeve gastrectomy (LSG) are not well described. Our objective was to determine the rate of nephrolithiasis after LRYGB versus LSG.MethodsThe electronic medical records of patients who underwent LRYGB or LSG between 2001 and 2017 were retrospectively reviewed.Results1,802 patients were included. Postoperative nephrolithiasis was observed in 133 (7.4%) patients, overall, and 8.12% of LRYGB (122/1503) vs. 3.68% of LSG (11/299) patients (P < 0.001). Mean time to stone formation was 2.97 ± 2.96 years. Patients with a history of UTI (OR = 2.12, 95%CI 1.41–3.18; P < 0.001) or nephrolithiasis (OR = 8.81, 95%CI 4.93–15.72; P < 0.001) were more likely to have postoperative nephrolithiasis.ConclusionThe overall incidence of symptomatic nephrolithiasis after bariatric surgery was 7.4%. Patients who underwent LRYGB had a higher incidence of nephrolithiasis versus LSG. Patients with a history of stones had the highest risk of postoperative nephrolithiasis. |
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Keywords: | Nephrolithiasis Bariatric surgery Gastric bypass Sleeve gastrectomy Hyperoxaluria |
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