Histological Study on Bone Remodeling of Aged Human Mandibular Condyles —Investigation Using Back-scattered Electron and Transmission Electron Microscopy— |
| |
| Institution: | 1. School of Civil Engineering, Shenyang Jianzhu University, Shenyang 110168, PR China;2. Department of Civil Engineering, Tsinghua University, Beijing 100084, PR China;3. School of Engineering, University of Bradford, BD7 1DP, UK;1. Institute for Infrastructure Engineering, University of Western Sydney, Penrith, NSW 2751, Australia;2. Department of Civil Engineering, Shandong Polytechnic, Jinan 250013, China;3. Department of Civil Engineering, Tsinghua University, Beijing 100084, China;1. Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal;2. ICVS/3B''s - PT Government Associate Laboratory, Braga, Guimarães, Portugal;3. Cardiology Department, Hospital of Braga, Braga, Portugal |
| |
| Abstract: | It is considered that osteoarthritis mainly affects articular cartilage, and the pathological mechanism involves both degenerative changes of the cartilage and bony changes. However, it has been indicated that the human temporomandibular joint has a higher capacity for remodeling. The causes and mechanisms of bony changes of human mandibular condyles have been a matter of speculation. In this study, we investigated human mandibular condyles by employing various microscopic investigations involving an electron probe micro analyzer and transmission electron microscope in addition to light microscopic observation. The results indicate that adaptive bony changes in the functional articular surface of mandibular condyles are brought about by cartilage calcification. Furthermore, the findings of cartilage calcification suggest the possibility of matrix-vesicle-mediated mineralization in the remodeling of aged human mandibular condyles. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
