二尖瓣反流对压差减半时间法测量瓣口面积的影响

目的探讨二尖瓣狭窄伴反流的患者用压差减半时间（PHT）法测量二尖瓣口面积的应用价值。方法43例风湿性心脏病二尖瓣狭窄合并轻、中度反流的患者，其中15例合并心房颤动，以PHT法、二维超声测量法分别测量二尖瓣口面积，并与心导管所得结果比较。比较三种方法测量结果的一致性。结果两种超声测量方法与心导管测量结果间的差别无显著性意义。PHT法、二维超声测量法的结果均与导管法呈正相关，相关系数分别为0．76（P〈0．05）、0．71（P〈0．05）。PHT法与导管法的相关性高于二维超声测量法。结论对二尖瓣狭窄合并轻、中度反流患者，PHT法测量瓣口面积有临床应用价值。

Effect of mitral regurgitation on mitral valvule area evaluated by Doppler pressure half-time

Objective To explore the clinical application of pressure half-time(PHT) method on rheumatic mitral stenosis coexisting mitral regurgitation. Methods Forty-three consecutive patients with rheumatic mitral stenosis coexisting mitral regurgitation, 15 of them in atrial fibrillation were studied, whose valve areas were determined by planimetry and Doppler PHT methods. The results were compared with those obtained invasively from cardiac catheter,and the reproducibility was assessed between the three measures. Results There was no statistical difference between the results of two ultrasound methods and those from cardiac catheter. Compared with the invasively determined mitral valve orifice area(MVOA), PHT method(r= 0.76) had the better agreement than that of planimetry method(r= 0.71)(P< 0.05). Conclusions Doppler PHT method is an accurate and feasible technique in evaluating MVOA in patients with rheumatic mitral stenosis coexisting mild or moderate mitral regurgitation.