Nicotine and caffeine effects on the task-elicited blood pressure response |
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| Authors: | R L Ray M J Nellis J V Brady R W Foltin |
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| Affiliation: | 1. Service de pharmacologie médicale, université de Bordeaux, UMR 1219, 33076 Bordeaux cedex, France;2. Service de pharmacologie médicale, pôle de santé publique, CHU de Bordeaux, 33000 Bordeaux, France;3. Department of medical pharmacology and toxicology, CHU Montpellier university hospital, 34090 Montpellier, France;4. Laboratory of biostatistics, epidemiology and public health (EA 2415), faculty of medicine, university of Montpellier, 34090 Montpellier, France;1. Department of Nursing, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China;2. Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu, Sichuan, People''s Republic of China;3. Department of Health Policy and Management, West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China;4. Institute for Disaster Management and Reconstruction (IDMR), Sichuan University, Chengdu, Sichuan, China;5. Department of Health Behavior and Social Medicine, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China;6. School of Resources and Environmental Science, Wuhan University, Wuhan, China;7. International Institute of Spatial Lifecourse Epidemiology (ISLE), Hong Kong, China;1. State Key Laboratory for Fabrication & Processing of Nonferrous Metals, Beijing General Research Institute for Nonferrous Metals, No.2, Xinjiekouwai Street, Beijing 100088, China;2. State Key Laboratory for Performance and Structural Safety of Petroleum Tubular Goods and Equipment Materials, CNPC Tubular Goods Research Institute, No.89, Jinye 2ndRoad, Xi''an, Shaanxi 710077, China |
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| Abstract: | Nine subjects participated in four daily sessions during which a psychomotor task was performed prior to and following drug administration. Blood pressure was reliably increased by task performance, cigarette smoking, and caffeine administration. The effect of the combination of task performance, cigarette smoking and caffeine administration was additive, resulting in a markedly increased blood pressure during task performance for subjects smoking cigarettes and receiving caffeine. |
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