| 应用原子力显微镜对口腔变异链球菌黏附机制的研究 |
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| 引用本文： | 盖阔,郝丽英,蒋丽. 应用原子力显微镜对口腔变异链球菌黏附机制的研究[J]. 国际口腔医学杂志, 2017, 44(3). DOI: 10.7518/gjkq.2017.03.014 |
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| 作者姓名： | 盖阔 郝丽英 蒋丽 |
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| 作者单位： | 口腔疾病研究国家重点实验室,国家口腔疾病临床研究中心,四川大学华西口腔医院 成都 610041 |
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| 基金项目： | 国家自然科学基金，四川省科技计划项目(2016FZ0069)This study was supported by National Natural Science Foundation of China，The Planned Science and Technology Project of Sichuan Province |
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| 摘 要： | 原子力显微镜(AFM)是一种理想的探测细菌与生物材料之间基本相互作用力及研究微生态系统形态和力学的工具,被应用于包括口腔变异链球菌在内的多种微生物的形态及力学研究中.本文就AFM在口腔变异链球菌黏附研究中的应用及在相关黏附机制、黏附影响因素等方面的研究成果进行综述,总结阐述口腔变异链球菌黏附的分子生物学机制,为细菌黏附的研究提供力学基础及新思路.
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| 关 键 词： | 原子力显微镜 变异链球菌 细菌黏附 |
Study of the adhesion mechanism of oral Streptococcus mutans based on atomic force microscope |
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| Gai Kuo,Hao Liying,Jiang Li.. Study of the adhesion mechanism of oral Streptococcus mutans based on atomic force microscope[J]. Journal of International Stomatology, 2017, 44(3). DOI: 10.7518/gjkq.2017.03.014 |
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| Authors: | Gai Kuo Hao Liying Jiang Li. |
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| Abstract: | Atomic force microscope(AFM) is an ideal tool for detecting the fundamental interactions between bacteria and biomaterials and studying the morphology and mechanics of microsystems including oral Streptococcus mutans. In this paper, the application of AFM in study of the adhesion mechanisms and influencing factors are reviewed, which summarizes the molecular mechanism of the adhesion of oral Streptococcus mutans. Thus, it provides mechanical basis and a new way for studying bacterial adhesion. |
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| Keywords: | atomic force microscope Streptococcus mutans bacterial adhesion |
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