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Kiss-1 基因与恶性肿瘤转移
引用本文:马小开. Kiss-1 基因与恶性肿瘤转移[J]. 国际肿瘤学杂志, 2009, 36(11). DOI: 10.3760/cma.j.jssn.1673-422X.2009.11.010
作者姓名:马小开
作者单位:蚌埠医学院第一附属医院肿瘤外一科,233004
摘    要:Kiss-1基因是与人类多种恶性肿瘤发生发展相关的肿瘤转移抑制基因,在恶性肿瘤的浸润和转移过程中发挥重要作用.Kiss-1基因与黑色素瘤、乳腺癌、胃癌、食管癌及分化型甲状腺癌等恶性肿瘤的转移密切相关,但其作用机制尚未完全清楚.通过检测恶性肿瘤患者肿瘤组织中Kiss-l基因的表达情况,将有助于恶性肿瘤患者的治疗和预后评估.

关 键 词:肿瘤  转移  Kiss-1基因

Kiss-1 gene and metastasis of malignant tumor
MA Xiao-kai. Kiss-1 gene and metastasis of malignant tumor[J]. Journal of International Oncology, 2009, 36(11). DOI: 10.3760/cma.j.jssn.1673-422X.2009.11.010
Authors:MA Xiao-kai
Abstract:Kiss-1 gene is an anti-oncogene which is correlative with the genesis and progress of various human malignant tumors.it plays an important role in process of tumor invasion and metastasis. Kiss-1 gene is associated closely with metastasis of melanoma,breast cancer,gastric carcinoma,esophageal cancer and differentiated thyroid carcinoma and so on,but the mechanism is not fully elucidated. Therefore,the detection of Kiss-1 gene expression will be valuable for the treatment and prognosis of malignant tumor.
Keywords:Neoplasms  Metastasis  Kiss-1 gene
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