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| RNA干涉技术在哺乳类细胞和人类疾病基因功能研究中的应用 | |
| 引用本文： | 郭丹,傅更锋,樊燕蓉,薛龙增,徐根兴,王建军.RNA干涉技术在哺乳类细胞和人类疾病基因功能研究中的应用[J].生物医学工程学杂志,2004,21(1):138-140. |
| 作者姓名： | 郭丹 傅更锋 樊燕蓉 薛龙增 徐根兴 王建军 |
| 作者单位： | 1. 南京大学,生命科学学院,南京,210093;第二军医大学,南京军医学院,南京,210049 2. 第二军医大学,南京军医学院,南京,210049 3. 南京大学,生命科学学院,南京,210093 |
| 摘 要： | RNA干涉技术是一种很有潜力的研究基因功能的新技术 ,它具有快捷、方便、高效和特异性高等特点 ,但用此技术研究哺乳类动物细胞基因功能和人类疾病相关基因功能才刚刚起步 ,本文对该技术在哺乳类细胞和人类疾病基因功能中的研究进展进行了评述 |
| 关 键 词： | RNA干涉 基因沉默 小干涉RNA RNAi siRNA |
Application of RNA Interference Technique in the Research of Mammalian Cells and Human Disease |
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| Guo Dan , Fu Gengfeng , Fan Yanrong Xue Longzeng Xu Genxing , Wang Jianjun.Application of RNA Interference Technique in the Research of Mammalian Cells and Human Disease[J].Journal of Biomedical Engineering,2004,21(1):138-140. | |
| Authors: | Guo Dan Fu Gengfeng Fan Yanrong Xue Longzeng Xu Genxing Wang Jianjun |
| Institution: | Nanjing Military Medical College, Second Military Medical University, Nanjing, China. |
| Abstract: | RNA interference provides a new approach for elucidation of gene function. It holds the advantages of quickness, convenience, high effect and high specificity. In spite of these, the application of RNA interference technique in studying the mammalian cells and human disease is still in the beginning. In this paper, a review of the development of RNA interference in mammalian cells and human disease is presented. |
| Keywords: | RNA interference Gene silencing Small interfering RNA RNAi siRNA |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |