耐碳青霉烯类鲍曼不动杆菌同源性研究

目的探讨我院2001年8月至2002年3月显著增多的耐碳青霉烯类鲍曼不动杆菌之间的同源性.方法用脉冲场凝胶电泳对7株耐碳青霉烯类鲍曼不动杆菌进行分型,明确其是否为同一菌株的克隆.结果7株不动杆菌分为:A型2株,A1型2株,A2型1株.A1型与A2型之间的相似系数达94.6%,它们与A型的相似系数达84.9%,其余两株各有独特的PFGE分型.结论其中5株耐碳青霉烯类鲍曼不动杆菌有高度同源性,第5号株极可能是此次院内感染的源头.

The homogeneity of carbapenem-resistant acinetobacter baumannii

Objective To investigate the homogeneity of the unusually ever-increasing carbapenm-resistant(CR)Acinetobacer baumannii isolates selected from August 2001 to March 2002 in ShenZhen people's hospital. Methods The pulse-field gel electrophoresis(PFGE) was used to type 7 CR Acinetobacter isolates gathered in our hospital,determing whether they derived from the same clone. Results 7 isolates was identified to these PFGE types :2 for type A,2 for type A 1,1 for type A 2.The similarity coeffient between A 1 and A 2 was 94.6%, 84.9% between A 1(A 2)and A. The other two isolates showed distinct PFGE types. Conclusions The five CR Acinetobacter baumannii isolates were closely related. The finding highly suggests that V isolate is the source of the nosocomial infection.