NBCA栓塞治疗脑动静脉畸形并发症分析

目的探讨NBCA栓塞治疗脑动静脉畸形(AVM)的并发症的发生率及高危因素.方法回顾性研究469例施行NBCA栓塞治疗的脑AVM的临床和影像学资料,总结并发症的情况以及分析他们的血管构筑学特征.结果469例脑AVM共行1108次栓塞,每例栓塞1～8次,平均2.3次;共发生并发症11例(出血性并发症4例,缺血性并发症7例),其中死亡2例,植物生存l例,轻度永久性神经功能缺损1例,短暂性神经功能缺损7例.结论本组脑AVM行NBCA栓塞治疗有较低的手术相关并发症.但对于栓塞高危病人,应采取特殊的栓塞策略.

Complications of 469 brain arteriovenous malformations treated with N-butyl cyanoacrylate

Objective To probe into incidence and risk factors of complications of brain arteriovenous malformation (AVM) following N-butyl cyanoacrylate (NBCA) embolization. Methods All clinical data and image findings of 469 brain AVM patients who underwent embolization with NBCA were studied retrospectively. The complications and their relation to their angiographic features were summed up. Results The 469 patients accepted totally 1108 endovascular embolization, each with 1~8 times (average 2.3 times). 11 patients developed treatment-related complications, including 4 hemorrhagic and 7 ischemic complications. Of these 11 cases, 2 died, 1 had vegetative state, 1 mild permanent functional deficit and other 7 temporary neurological deficits. Conclusion The patients of brain AVM treated with NBCA embolization have fewer treatment-related complications, but the ones who have high risk of embolization should be treated with special embolization strategies.