| 血浆脂蛋白相关磷脂酶A2检测对颈动脉斑块稳定性的预测价值 |
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| 引用本文： | 费世早,王磊,庞洪波,陈观保,储照虎.血浆脂蛋白相关磷脂酶A2检测对颈动脉斑块稳定性的预测价值[J].脑与神经疾病杂志,2012,20(1):44-46. |
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| 作者姓名： | 费世早 王磊 庞洪波 陈观保 储照虎 |
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| 作者单位： | 1. 芜湖市第二人民医院神经内科,安徽,241000
2. 皖南医学院弋矶山医院神经内科 |
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| 摘 要： | 目的检测动脉粥样硬化脑梗死(ACI)患者及健康体检者血浆脂蛋白相关磷脂酶A2(Lp-PLA2)水平,探讨颈动脉斑块稳定性与血浆Lp-PLA2水平相关性。方法采用双抗体夹心酶联免疫吸附法(ELISA)检测血浆Lp-PLA2水平,同时检测血脂、纤维蛋白原等生化指标;行颈动脉彩色多普勒超声检查,评估颈动脉斑块稳定性。结果不稳定斑块组血浆Lp-PLA2水平明显高于稳定斑块组(P<0.01)。结论血浆Lp-PLA2水平可作为颈动脉斑块稳定性的预测指标。
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| 关 键 词： | 动脉粥样硬化脑梗死 脂蛋白相关磷脂酶A2 颈动脉斑块 |
The predictive value of lipoprotein-associated phospholipase A2 in carotid artery plaque stability |
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| FEI Shi-zao,WANG Lei,PANG Hong-bo,CHEN Guan-bao,CHU Zhao-hu.The predictive value of lipoprotein-associated phospholipase A2 in carotid artery plaque stability[J].Journal of Brain and Nervous Diseases,2012,20(1):44-46. |
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| Authors: | FEI Shi-zao WANG Lei PANG Hong-bo CHEN Guan-bao CHU Zhao-hu |
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| Institution: | .Department of Neurology,No.2 People’s Hospital of Wuhu,Wuhu 241000,China |
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| Abstract: | Objective To observe the levels of plasma lipoprotein-associated phospholipase A2(Lp-PLA2) in atherosclerotic cerebral infarction and healther people,analysis of plasma Lp-PLA2 levels with carotid artery plaque stability.Methods Plasma Lp-PLA2 levels were detected by enzyme linked immunosorbent assay(ELISA),and the levels of blood lipids and fibrinogen,The carotid plaque stability were determined by cervical vascular color Dopplerultrasound.Rseults As compared to the vulnerable plaque group,the levels of plasma lipoprotein-associated phospholipase A2(Lp-PLA2) were higher in stable plaque group(P<0.01).Conclusion Lp-PLA2 serves as a predictive indicator of carotid artery plaque stability. |
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| Keywords: | Atherosclerotic cerebral infarction Lipoprotein-associated phospholipase A2 Carotid artery plaque |
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