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脑出血患者心肌酶谱与纤维蛋白原联合检测的临床价值
引用本文:王喜栋,张琳,李伟,张瑞. 脑出血患者心肌酶谱与纤维蛋白原联合检测的临床价值[J]. 脑与神经疾病杂志, 2012, 20(1): 37-39
作者姓名:王喜栋  张琳  李伟  张瑞
作者单位:河北医科大学第二医院检验科,石家庄,050000
摘    要:目的探讨急性脑出血后患者心肌酶谱及纤维蛋白原的早期预警作用。方法收集我院住院就诊的47例脑出血患者为病例组,另选50例健康体检者为对照组。用Roche-P800生化分析仪检测心肌酶谱,用ACL-TOP全自动凝血分析仪检测纤维蛋白原。观察病例组与对照组的心肌酶谱及纤维蛋白原的水平,并进行比较分析两者联合检测的临床意义。结果与对照组比较,病例组的心肌酶谱及纤维蛋白原明显升高(P<0.05)。结论急性脑出血患者的心肌酶谱和纤维蛋白原的异常升高对合并心肌受损有早期预测价值,联合监测心肌酶谱和纤维蛋白原可为临床早期采取治疗措施提供实验依据。

关 键 词:脑出血  心肌酶  纤维蛋白原  ROC曲线

The clinical significance of combined detection of myocardial enzymes and fibrinogen in patients with cerebral hemorrhage
WANG Xi-dong,ZHANG Lin,LI Wei,ZHANG Rui. The clinical significance of combined detection of myocardial enzymes and fibrinogen in patients with cerebral hemorrhage[J]. Journal of Brain and Nervous Diseases, 2012, 20(1): 37-39
Authors:WANG Xi-dong  ZHANG Lin  LI Wei  ZHANG Rui
Affiliation:.Department of Clinical Laboratory,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China
Abstract:Objective To investigate the early warning role of myocardial zymogram and fibrinogen in patients after acute cerebral hemorrhage.Methods Fourty-seven cases with acute cerebral hemorrhage were collected and,other 50 healthy volunteers as control group.Myocardial enzymes were determined by Roche-P800 biochemical analyzer and fibrinogen was detected by ACL-TOP automatic coagulation analyzer.To observe the level of myocardial enzyme and fibrinogen in both case and control groups and analyse the clinical significance of combined detection of myocardial enzymes and fibrinogen.Results Compared with control group,the level of myocardial enzymes and fibrinogen in cerebral hemorrhage group was increased significantly(P<0.05).Conclusion The abnormal elevation of myocardial enzymes and fibrinogen in patients with cerebral hemorrhage has predictive value of early myocardial damage.Combined detection of myocardial enzymes and fibrinogen may provide the theoretical basis for the clinical early treatment.
Keywords:Cerebral hemorrhage  Myocardial enzymes  Fibrinogen  ROC curve
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