| 自体骨或硫酸钙人工骨结合MC+~椎间融合器在颈椎前路融合中的应用:疗效及并发症比较 |
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| 引用本文： | 陈同磊,成茂华,沈忆新,言湛军,连晓宁,董启榕. 自体骨或硫酸钙人工骨结合MC+~椎间融合器在颈椎前路融合中的应用:疗效及并发症比较[J]. 中国组织工程研究与临床康复, 2010, 14(4). DOI: 10.3969/j.issn.1673-8225.2010.04.035 |
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| 作者姓名： | 陈同磊 成茂华 沈忆新 言湛军 连晓宁 董启榕 |
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| 作者单位： | 1. 苏州大学附属第二医院骨科,江苏省,苏,州,市,215004
2. 苏州大学基础医学与生物科学学院细胞分子生物学教研室,江苏省苏州市,215123 |
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| 摘 要： | 背景:自体骨在颈椎植骨融合术中应用最早、最多,但其来源有限,同时也带来供骨区感染、出血、术后疼痛等并发症.近年来随着新型植骨融合材料的使用,使上述并发症得以避免或减少.目的:比较MC+~R 椎间融合器结合自体骨与硫酸钙人工骨在颈椎前路融合中的临床效果.方法:于2008-01/12对26例脊髓型颈椎病患者共34个节段实施前路椎间盘摘除、椎体融合术,取颈前斜切口3.0-4.0 cm,切除椎间盘及后纵韧带,保留终板,自体骨组椎间融合器填充自体髂骨松质骨,硫酸钙组椎间融合器填充Wright公司OsteoSet人工骨,结合固定嵌片使用.以术后X射线片和JOA评分及术后Odom's疗效评定标准评价疗效.结果与结论:两组共26例患者(34个节段)全部获得随访,术后两组JOA评分无明显差异,术后两组临床疗效评定(Odom's标准)优良率,硫酸钙组高于自体骨组,但差异无显著性意义(p>0.05).术后3,6个月人工骨组融合率比自体骨组低,但12个月时两组融合率均为100%.硫酸钙组术后6个月前凸角丢失较自体骨组多0.4°,两组间比较差异无显著性意义(p>0.05).提示硫酸钙结合MC+ 椎间融合器与自体骨结合MC+ 椎间融合器治疗脊髓型颈椎病的临床疗效一致,但硫酸钙人工骨可以有效避免取骨区并发症.
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| 关 键 词： | 脊髓型颈椎病 聚醚醚酮 硫酸钙人工骨 生物材料 硬组织植入物 |
Application of MC+~(R) combined with autogenous bone or calcium sulfate artificial bone in anterior cervical fusion: Comparative study of therapeutic effects and complications |
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| Chen Tong-lei,Cheng Mao-hua,Shen Yi-xin,Yan Zhan-jun,Lian Xiao-ning,Dong Qi-rong. Application of MC+~(R) combined with autogenous bone or calcium sulfate artificial bone in anterior cervical fusion: Comparative study of therapeutic effects and complications[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2010, 14(4). DOI: 10.3969/j.issn.1673-8225.2010.04.035 |
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| Authors: | Chen Tong-lei Cheng Mao-hua Shen Yi-xin Yan Zhan-jun Lian Xiao-ning Dong Qi-rong |
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| Affiliation: | Chen Tong-lei1,Cheng Mao-hua1,Shen Yi-xin1,Yan Zhan-jun1,Lian Xiao-ning2,Dong Qi-rong11Department of Orthopaedics,Second Affiliated Hospital of Soochow University,Suzhou 215004,Jiangsu Province,China,2Cell , Molecular Biology Institute,College of Basic Medicine , Biological Science,Soochow University,Suzhou 215123 |
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| Abstract: | BACKGROUND: Autogenous bone has been used in cervical vertebra graft bone fusion in earliest stage and at most. However, its source is limited, simultaneously, induced many complications such as infection, hemorrhage and postoperative pain in the donor bone region. Recently, above-mentioned complications were avoided or reduced with the usage of new graft bone fusion material. OBJECTIVE: To compare clinical efficacy using MC+? combination of autogenous bone or calcium sulfate artificial bone in anterior cer... |
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