| 急进高海拔地区对大鼠某些组织中Mn－SOD、CuZn－SOD及LPO的影响 |
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| 引用本文： | 张晓林,刘衍国,张惠莉,王珺.急进高海拔地区对大鼠某些组织中Mn－SOD、CuZn－SOD及LPO的影响[J].解放军预防医学杂志,1994(2). |
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| 作者姓名： | 张晓林 刘衍国 张惠莉 王珺 |
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| 作者单位： | 青海医学院生化教研室 |
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| 摘 要： | 将大鼠快速由平原带至高原，其肺、肾组织Ｍｎ－ＳＯＤ，ＣｕＺｎ－ＳＯＤ活性明显降低，心脏的ＳＯＤ活性也呈下降趋势；心、肺、肾组织的ＬＰＯ含量显著升高。结果提示：急进高海拔地区、可引起体内抗氧化能力减弱，脂质过氧化反应增强。
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| 关 键 词： | 高原，锰－超氧化物歧化酶，铜锌－超氧化物歧化酶，脂质过氧化 |
^THE EFFECT OF FAST ASCENDING TO HIGH ALTITUDE ON Mn-SOD,Cu2n-SOD ACTIVITIES AND
LPO LEVELS IN RAT TISSUES |
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| Zhang Xiaolin, Liu Yanguo, Zhang Huili, Wang
Jun.^THE EFFECT OF FAST ASCENDING TO HIGH ALTITUDE ON Mn-SOD,Cu2n-SOD ACTIVITIES AND
LPO LEVELS IN RAT TISSUES[J].Journal of Preventive Medicine of Chinese People's Liberation Army,1994(2). |
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| Authors: | Zhang Xiaolin Liu Yanguo Zhang Huili Wang
Jun |
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| Abstract: | fter rapidly ascending
to high aItitude, the activities of Mn-SOD andCuZn-SOD in lung, kidney in rats decreased
significantly,the SOD activityin heart had a tendency of decrease,but LPO levels increased
significantlyin heart,lung and kidney of rats.These results indicated that the rapidlyascending to
high altitude can result in increase of lipid peroxidation andthe antioxidant defensive system
being injured in tissues. |
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| Keywords: | high altitude manganic superoxide dismutase copper zinc superoxide dismutase lipid peroxide level |
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