高血压视网膜病变危险因素分析

目的分析高血压视网膜病变发生的危险因素。方法比较视网膜病变组和无视网膜病变组的血压、空腹静脉血总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A(ApoA)、载脂蛋白B100(ApoB100)、血尿酸(UA)及尿微量白蛋白(mAlb)、β2-微球蛋白(β2-MG),α1-微球蛋白(α1-MG)等各项指标,并对各危险因素做Logistic回归分析。结果视网膜病变组的收缩压、舒张压、TG、UA、mAlb均显著高于无视网膜病变组(P<0.05),但Logistic回归分析显示以上因素都不是高血压视网膜病变的独立危险因素。结论高血压视网膜病变的发生受多种因素影响,预防除了要注意控制血压,定期检查眼底外还要注意监测血脂、UA及mAlb。

Analysis of risk factors to hyperpiesia retinopathy

Objective It is to analyze the risk factors of to hyperpiesia retinopathy.Methods The indexes of blood pressure,TC,TG,HDL-C,LDL-C,ApoA,ApoB100, blood uric acid,urine mAlb,β2-MG and α1-MG were compared between hyperpiesia patients with retinopathy and those without retinopathy.Then Logistic regression analysis was done on the above indexes.Results The indexes of SBP,DBP,TG, blood uric acid and urine mAlb in retinopathy group were all significantly higher than that in no-retinopathy group(P<0.05),but Logistic regression analysis showed that they were all not independent risk factors to hyperpiesia retinopathy.Conclusion The occurrence of hyperpiesia retinopathy can be influenced by many factors.To prevent hyperpiesia retinopathy,blood fat,blood uric acid and urine mAlb should be monitored except blood pressure control and periodic inspection of eyeground.