| 雷公藤主要植物化学成份对大鼠生殖器官的影响 |
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| 引用本文： | 李玲,张益鹄,黄光照. 雷公藤主要植物化学成份对大鼠生殖器官的影响[J]. 华中科技大学学报(医学版), 1988, 0(1) |
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| 作者姓名： | 李玲 张益鹄 黄光照 |
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| 作者单位： | 同济医科大学法医学系法医病理学教研室(李玲，张益鹄)，同济医科大学法医学系法医病理学教研室(黄光照) |
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| 摘 要： | 雷公藤总甙、总萜和总生物碱在中毒剂量下,均可引起大鼠睾丸生殖上皮退行住变性,其中以总碱组最为突出。精子细胞和精子最敏感,其次为精母细胞,精原细胞耐受性最强。小实验所见与棉酚所致睾丸损害颇相类似。三种植化成分对大鼠卵巢的损害较睾丸明显为轻。
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| 关 键 词： | 雷公藤 生殖器官 睾丸 |
Effects of the Main Components of Lei Gong Teng (Tripterygium Wilfordii Hook) on the Reproductive Organs in Rats |
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| Li Ling,Zhang Yigu,Huang Guangzhao. Effects of the Main Components of Lei Gong Teng (Tripterygium Wilfordii Hook) on the Reproductive Organs in Rats[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1988, 0(1) |
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| Authors: | Li Ling Zhang Yigu Huang Guangzhao |
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| Affiliation: | Li Ling,Zhang Yigu,Huang GuangzhaoDepartment of Forensic Pathology,Faculty o/ Forensic Medicine,Tongji Medical University,Wuhan |
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| Abstract: | The results of the present work showed that degenerative changes of the seminiferous tubules of testes could be induced by total glycosides (TG), total terpenes (TT) as well as total alkaloides (TA) of Lei Gong Teng (LGT). The lesions of testes in TA group were most prominent.The germinal cells in different stages of the testis were in varying degrees of degeneration and decreased in number. Spermatides and sperms were most susceptible to LGT, spermtoblasts were less susceptible, while spermatogonia were most resistant to LGT. The results suggested that TA have anti-spsrmatogenetic action similar to that of gossypol. The injurious, effects of the three main components of LGT on the ovary were much less evident than those on the testis. |
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| Keywords: | tripterygium wilfordii reproductive organs testis |
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