| 海红果黄酮对垂体后叶素致急性心肌缺血的保护作用 |
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| 引用本文： | 葛睿,李青山,赵亮. 海红果黄酮对垂体后叶素致急性心肌缺血的保护作用[J]. 实用口腔医学杂志, 2007, 36(4): 301-303 |
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| 作者姓名： | 葛睿 李青山 赵亮 |
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| 作者单位： | 山西医科大学药学院 (030001) |
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| 摘 要： | 目的初步研究海红果黄酮对大鼠急性心肌缺血的保护作用。方法用垂体后叶素制备心肌缺血大鼠模型,观察造模前后Ⅱ导联心电图T波、S点、P-P间期的变化,检测造模前后血清超氧化物歧化酶(SOD)、丙二醛(MDA)含量的变化。结果海红果黄酮各剂量组均可对抗垂体后叶素引起的心电图变化,且对血清SOD、MDA含量的变化都有明显的对抗作用(P<0.05,P<0.01)。结论海红果黄酮对实验性急性心肌缺血具有良好的保护作用。
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| 关 键 词： | 心肌缺血 垂体激素类,后叶 海红果黄酮 |
| 修稿时间： | 2006-11-15 |
The protective effects of Haihongguo flavonoids on the injury myocardial ischemia induced by pituitrin |
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| GE Rui,LI Qing-shan,ZHAO Liang. The protective effects of Haihongguo flavonoids on the injury myocardial ischemia induced by pituitrin[J]. Journal of Practical Stomatology, 2007, 36(4): 301-303 |
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| Authors: | GE Rui LI Qing-shan ZHAO Liang |
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| Affiliation: | Pharmaceutical Institute, Shanxi Medical University, Taiyuan 030001 ,China |
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| Abstract: | Objective To study the protective effects of Haihongguo flavonoids on the acute myocardial ischemia. Methods Acute myocardial ischemia model was induced by pituitrin. The parameters of T-wave, point S and P-P period of ECG were observed. The concentrations of SOD and MDA in the serum were measured. Results Compared with control group, the changes of T-wave, point S and P-P period of ECG in Haihongguo flavonoids groups were significantly antagonized, and the changes of concentrations of SOD and MDA in the serum were also counteracted remarkably. Conclusion Haihongguo flavonoids have a protective effect on the experimental myocardial ischemia of rats. |
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| Keywords: | Myocardial ischemia Pituitary hormones posterior Haihongguo flavonoids |
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