| Toll样受体与肾脏疾病 |
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| 引用本文： | 张瑜,周建华. Toll样受体与肾脏疾病[J]. 临床儿科杂志, 2007, 25(1): 71-73 |
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| 作者姓名： | 张瑜 周建华 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院儿科,湖北武汉,430030;华中科技大学同济医学院附属同济医院儿科,湖北武汉,430030 |
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| 摘 要： | Toll样受体（Toll-1ikereceptors，TLRs）作为一类病原模式识别受体在免疫应答和炎症反应中发挥重要作用。新近研究表明，TLRs家族的成员可能参与介导炎症性肾脏病和泌尿系统感染性疾病的发生。现就TLRs的生物学特征及其与肾脏疾病的关系等方面予以综述。
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| 关 键 词： | Toll样受体 肾脏疾病 生物学特征 |
| 文章编号： | 1000-3606（2007）01-071-03 |
| 收稿时间： | 2005-12-20 |
| 修稿时间： | 2005-12-20 |
Toll-like receptors and kidney diseases |
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| ZHANG Yu,ZHOU Jian-hua. Toll-like receptors and kidney diseases[J]. The Journal of Clinical Pediatrics, 2007, 25(1): 71-73 |
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| Authors: | ZHANG Yu ZHOU Jian-hua |
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| Affiliation: | Department of Pediatrics, Tonal Hospital Afftliated to Tongji Medical School, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China |
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| Abstract: | Toll- like receptors (TLRs),a family of pathogen recognition receptors,play an important role in immune responses and inflammation. It has been recently demonstrated that members of the TLR family are involved in immune- mediated renal diseases and urinary tract infections. The biological characteristics of TLRs and their roles in the pathogenesis of kidney diseases were discussed in this review. |
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| Keywords: | Toll-like receptors kidney diseases biological characteristica |
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