| 大鼠部分肝移植动物模型制备及技术改进 |
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| 引用本文： | 王跃全,张培建,王红鲜. 大鼠部分肝移植动物模型制备及技术改进[J]. 陕西医学杂志, 2005, 34(6): 647-649 |
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| 作者姓名： | 王跃全 张培建 王红鲜 |
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| 作者单位： | 青海医学院附属医院普外科,西宁,810001 |
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| 基金项目： | 江苏省卫生厅医学重点学科(实验室)开放项目基金资助 |
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| 摘 要： | 目的:建立稳定、可靠的大鼠部分肝移植动物模型。方法:在大鼠原位全肝移植实验的基础上,参照Steinbauer等的方法建立大鼠部分肝移植动物模型。对80只SD大鼠施行40例部分肝移植,并在大鼠部分肝移植的麻醉、手术操作技巧和术前、术后处理等方面进行了改进。结果:肝移植大鼠术后成活率90%,1周以上存活率60%。结论:改进后的大鼠部分肝移植模型,成活率高,重复性好,可作为部分肝移植有关实验研究的可靠、稳定的动物模型。
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| 关 键 词： | 肝移植 移植,同种 动物,实验 大鼠 |
Establishment of rat model of the partial liver transplantation with some technical improvement |
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| Wang Yuequan,Zhang Peijian,Wang Hongxian. Establishment of rat model of the partial liver transplantation with some technical improvement[J]. Shaanxi Medical Journal, 2005, 34(6): 647-649 |
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| Authors: | Wang Yuequan Zhang Peijian Wang Hongxian |
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| Affiliation: | Xining810001 |
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| Abstract: | Objective: To establish a stable and reliable rat model of the partial liver transplantation. Methods: Based on the success of orthotopic liver transplantation model, we established the rat model of the partial living donor liver transplantation with Steinbauer methods. Results :The survival rate after operation was 90%, above one week was 60%. Conclusion:The improved rat model can be used as a more reliable and stable experimental model for higher survival rate and repeatability. |
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| Keywords: | Liver transplantation Transplantation homologous Animals laboratory Rats |
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