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哈尔滨市2009-2010年流感监测分析
引用本文:蔡秀芝, 肖凤娟, 孙波, 颜洪海, 潘玉辉, 赵景波. 哈尔滨市2009-2010年流感监测分析[J]. 中国公共卫生, 2011, 27(1): 8-9. DOI: 10.11847/zgggws2011-27-01-04
作者姓名:蔡秀芝  肖凤娟  孙波  颜洪海  潘玉辉  赵景波
作者单位:1.哈尔滨医科大学, 黑龙江 哈尔滨 150081;;2.哈尔滨市疾病预防控制中心传染病预防控制所
摘    要:目的 了解黑龙江省哈尔滨市2009-2010年度流感流行趋势及其病毒株变化特点,为本地区防控流感提供科学依据.方法 通过《哈尔滨市流感监测信息系统》统计21家流感监测哨点医院流感样病例(ILI)数据及18家流感监测哨点学校ILI数、因感冒缺课人数,采集哨点医院部分ILI咽拭子标本,用实时荧光聚合酶链反应(RT-PCR)分子生物学方法和鸡胚或狗肾细胞(MDCK)培养方法进行病毒分离,采用血凝抑制实验对分离的流感毒株进行型别鉴定.结果 2009-2010年度,哈尔滨市21家哨点医院门(急)诊共报告ILI数27 524例,ILI就诊率为9.57%;18家哨点学校共报告ILI数4 239例,ILI占总监测人次百分比为0.23%,因感冒缺课人数17 132例,占0.94%;采集ILI咽拭子标本929份,分离出阳性毒株84份,阳性率为9.04%,其中甲型H1N1型59株、B型22株、季甲H3型3株,分别占70.24%、26.19%、3.57%;2009-2010年度哈尔滨市ILI出现2个高峰,分别是2009年10月份第43周,ILI%峰值为21.06%和2010年1月份第4周,ILI%峰值为9.76%.2009年第49周之前甲型H1N1型流感毒株为优势株,第50周开始B型流感毒株为优势株.结论 ILI流行高峰与流感毒株检出高峰基本一致;流感流行高峰与2009年全球性甲型H1N1流感大流行有直接关系.

关 键 词:流感  流感样病例(ILI)  监测  流感毒株型别
收稿时间:2010-05-10

Influenza surveillance in Harbin city from 2009 to 2010
CAI Xiu-zhi, XIAO Feng-juan, SUN Bo, . Influenza surveillance in Harbin city from 2009 to 2010[J]. Chinese Journal of Public Health, 2011, 27(1): 8-9. DOI: 10.11847/zgggws2011-27-01-04
Authors:CAI Xiu-zhi  XIAO Feng-juan  SUN Bo
Affiliation:1.Department of Infectious Disease Control, Harbin Municipal Center for Disease Control and Prevention, Heilongjiang Province Harbin 150081, China
Abstract:Objective To study the trend of influenzainc idence from 2009 to 2010 in Harbin city and to analyze the dominantc irculating influenza virus in different sea sons for influenza prevention.Methods Data were collected from records of Harb in Influenza Surve illance System, including the number of influenza like illness(ILI) cases and school absen tees due to influenza from 21 sentinel hospitals and 18 sentinel schools in the surve illance system.To tally 929 nasopharyngeal swabsam ples from influenza like patientswere collected and tested with RT PCR.Processed specmiens were inoculated into chiken embryo or Madin Darby carine kidney(MDCK) cell culture for virus isolation.The types of the stra in sisolated were identified with hemagg lutination inhibition test.Results A total of 27 524 influenza like illness cases were reported by the 21 hospitals from 2009 to 2010 with a attendance rate of 9.57%.To tally 4 239 influenza like illness cases and 17 132 absen tees were reported by the 18 schools, respectively, accounting for 0.23% and 0.94% of the whole surve illance population.Eighty fourvirus strains were isolated from 929 nasopharyngeal swab samples with a positive rate of 9.04%, among which 59(70.24%) were type A(H1N1), 22(26.19%) type B, and 3(3.57%) seasonal influenza A3.There were two peaks of ILI during the study period.The first appeared in the 43th week(Oct 2009) with the highest ILI ratio of 21.06%, and the second appeard in the 4th week(Jan 2010) with the highest ILI ratio of 9.76%.H1N1 remained the dominant circulating influenza virus until the 50th week, followed by type B in fluenza virus.Conclusion The highest positive rate of influenza virus during the ILI peaks and a differential trend of influenzainc idence were observed which maybe possibly attributed to the pandemic influenza A(H1N1) virus in Harbin city in 2009.
Keywords:in fluenza  influenza like illness  surveillance  type of influenza virus strain
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