原发性输卵管癌手术治疗64例分析

[目的]探讨手术治疗在输卵管癌治疗中的重要性。[方法]回顾分析1990年1月至2006年6月浙江省肿瘤医院收治的原发性输卵管癌64例临床资料。[结果]64例输卵管癌的5年生存率56．25％。52例分期手术患者和12例无分期手术患者的3年、5年生存率差异有显著性（84．61％vs58．32％，P=0．0429；65．38％vs33．32％，P=0．043）；23例满意肿瘤细胞减灭术和14例不满意细胞减灭术患者的的3年、5年生存率差异有显著性（89．47％vs66．67％，P=0．0466；68．42％vs35．67％，P=0．04441。41例盆腔淋巴结清扫术和23例无盆腔淋巴结清扫术患者的3年、5年生存率之间无显著性差异（84．21％vs69．23％，P=0．4667；63．16％vs53．84％，P=0．459）。[结论]分期手术、满意的肿瘤细胞减灭术是影响输卵管癌预后的重要因素。盆腔淋巴结清扫术在输卵管癌分期手术和细胞减灭中是必要和可行的。

Surgical Treatment in 64 Cases with Primary Fallopian Tube Carcinoma

Purpose To explore the importance of surgery in primary fallopian tube carcinoma (PFTC). Methods Sixty-four cases with PFTC treated in Zhejiang cancer hospital from Jan. 1990 to Jun. 2006.The clinicopathological data were retrospectively analyzed. Results Five-year survival rate of 64 cases was 56.25%. There were significant difference in 3-, and 5-year survival rate between case with surgical staging (52 cases) and without no surgical staging (12 cases) (84.61% vs. 58.32%, P=0.0429; 65.38% vs. 33.32%, P=0.043), between optimal (23 cases) and suboptimal cytoreduction (14 cases) (89.47% vs. 66.67%, P=0.0466; 68.42% vs. 35.67%, P=0.0444). There was no significant difference in 3-, and 5-year survival rate between cases with (41 cases) and without pelvic lymphadenectomy (23 cases) (84.21% vs. 69.23%, P=0.4667; 63.16% vs. 53.84%, P=0.459). Conclusion Surgical staging, optimal cytoreduction are important factors on prognosis in PFTC. Pelvic lymphadenectomy is necessary and feasibility for surgical staging and cytoreduction.