| 糖尿病足患者血浆活化蛋白C抵抗、蛋白C和蛋白S活性的测定 |
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| 引用本文： | 侯慧珍,司廷林.糖尿病足患者血浆活化蛋白C抵抗、蛋白C和蛋白S活性的测定[J].医学检验与临床,2008,19(3). |
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| 作者姓名： | 侯慧珍 司廷林 |
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| 作者单位： | 山东中医药大学第二附属医院 |
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| 摘 要： | 目的探讨PC、PS活性的变化在糖尿病足形成中的作用和临床意义,以及APCR与糖尿病足形成的关系。方法采用Dahlback法对50例健康成年人(对照组)及60例糖尿病足患者(DF1、DF2组)进行APCR阳性率测定,同时测定受检者蛋白C(PC,)和蛋白S(PS)。结果糖尿病足(DF)患者血浆PC/PS活性下降与对照组有显著性差异。结论血浆PC/PS活性检测对糖尿病足患者的诊断、估计预后和疗效观察有参考价值,且APCR阳性者有动脉血栓发生的倾向。
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| 关 键 词： | 糖尿病足 蛋白C 蛋白S 活化蛋白C抵抗 |
Determination of Activity on Activated Protein C Resistance,Protein C and Protein S for Diabetic Foot Patient's Blood Plasma |
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| Hou Huizhen,Si Tinglin.Determination of Activity on Activated Protein C Resistance,Protein C and Protein S for Diabetic Foot Patient''s Blood Plasma[J].Medical Laboratory Science and Clinics,2008,19(3). |
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| Authors: | Hou Huizhen Si Tinglin |
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| Institution: | Hou Huizhen; Si Tinglin; |
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| Abstract: | Objective The relation of APCR and diabetic foot,the action and clinic meaning of PC,PS s activity change on the formation of diabetic foot were discussed.Methods APCR(by Dahlback′s method),protein C(PC) and protein S(PS) were estimated in 50 healthy adults(controls) and 60 diabetic foot patients(DF1 and DF2).Results Significant difference exists between controls and DF groups.Conclusion Determination of activity of blood s PC and PS has reference value to the diagnoses,estimate prognoses and curative effec... |
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| Keywords: | Diabetic foot Protein C Protein S Activated protein C resistance |
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