Assessment of intracellular cytokines and regulatory cells in patients with autoimmune diseases and primary immunodeficiencies — Novel tool for diagnostics and patient follow-up |
| |
| Authors: | Liv T. Osnes Britt Nakken Edit Bodolay Peter Szodoray |
| |
| Affiliation: | 1. Institute of Immunology, Rikshospitalet, Oslo University Hospital, Oslo, Norway;2. Division of Clinical Immunology, Institute of Internal Medicine, University of Debrecen Medical and Health Science Center, Debrecen, Hungary |
| |
| Abstract: | Serum and intracytoplasmic cytokines are mandatory in host defense against microbes, but also play a pivotal role in the pathogenesis of autoimmune diseases by initiating and perpetuating various cellular and humoral autoimmune processes. |
| |
| Keywords: | AIRE, autoimmune regulator ApoA1, Alipoprotein A1 Breg, regulatory B cell CFS, chronic fatigue syndrome CVID, common variable immunodeficiency ECP, extracorporeal photochemotherapy EPO, erythropoietin G-CSF, granulocyte colony-stimulating factor HGF, hepatocyte growth factor IFN, interferon IL, interleukin IL-1Ra, interleukin-1 receptor alpha IPEX, immunodysregulation polyendocrinopathy enteropathy X-linked syndrome iTreg, induced regulatory T cell MCTD, mixed connective tissue disease ME, myalgic encephalitis NK, natural killer cell NKT, natural killer T cell nTreg, natural regulatory T cell PID, Primary immunodeficiency PM/DM, polymyositis/dermatomyositis RA, rheumatoid arthritis RAG, recombination activating genes SCID, severe combined immunodeficiency SLE, systemic lupus erythematosus SNHL, sensorineural hearing loss SS, Sjö gren's syndrome SSc, systemic sclerosis Tc, T-cytotoxic cell Th, T-helper cell TNF, Tumor necrosis factor Treg, regulatory T cell TPO, thrombopoietin UCTD, undifferentiated connective tissue disease U1RNP, U1 ribonucleoprotein |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
