| Maspin和Fas在50例宫颈癌中的表达及意义 |
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| 引用本文： | 王爱娇.Maspin和Fas在50例宫颈癌中的表达及意义[J].肿瘤学杂志,2011,17(2):84-86. |
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| 作者姓名： | 王爱娇 |
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| 作者单位： | 永康市妇幼保健院,浙江,永康,321300 |
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| 摘 要： | 目的]分析Maspin和Fas在宫颈癌中的表达及其与临床病理特征间的关系。方法]应用免疫组化法检测20例正常宫颈、20例宫颈上皮内瘤样变（CIN）、50例宫颈癌组织中Maspin和Fas的表达水平。结果]正常宫颈、CIN、宫颈癌组织中Maspin阳性表达率分别为85.0%（17/20）,65.0%（13/20）和36.0%（18/50）,三组间有显著性差异（χ2=15.1875,P〈0.05）;Fas的阳性表达率分别为90.0%（18/20）,50.0%（10/20）和38.0%（19/50）,三组间有显著性差异（χ2=15.5329,P〈0.05）。Maspin表达与宫颈癌组织学分化程度、FIGO分期、淋巴结转移有关（P〈0.05）,Fas表达与宫颈癌FIGO分期、淋巴结转移有关（P〈0.05）。结论]Maspin和Fas在宫颈癌中低表达,两者参与了宫颈癌的发生和发展。
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| 关 键 词： | Maspin Fas 宫颈上皮内瘤样病变 宫颈肿瘤 免疫组织化学 |
Expression of Maspin and Fas in 50 Cases with Cervical Cancer and its Significance |
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| WANG Ai-jiao.Expression of Maspin and Fas in 50 Cases with Cervical Cancer and its Significance[J].Journal of Oncology,2011,17(2):84-86. |
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| Authors: | WANG Ai-jiao |
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| Institution: | WANG Ai-jiao(Yongkang Maternity and Child Care Hospital,Yongkang 321300,China) |
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| Abstract: | Purpose] To investigate the expression of Maspin and Fas and its relationship with clinicopathological features in cervical carcinoma.Methods] The expression of Maspin and Fas in 20 cases of normal cervix tissues,20 cases of cervical intraepithelial neoplasia(CIN) tissues and 50 cases of cervical carcinoma tissues was detected by immunohistochemical method.Results] The positive rate of Maspin in normal cervix tissues,CIN tissues and cervical carcinoma was 85.0%(17/20),65.0%(13/20) and 36.0%(18/50),respec... |
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| Keywords: | Maspin Fas cervical intraepithelial neoplasia cervical neoplasms immunohistochemistry |
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