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Human dermal matrix scaffold augmentation for large and massive rotator cuff repairs: preliminary clinical and MRI results at 1-year follow-up
Authors:Roberto Rotini  Alessandro Marinelli  Enrico Guerra  Graziano Bettelli  Alessandro Castagna  Milena Fini  Elena Bondioli  Maurizio Busacca
Affiliation:(1) U.O.C. Malattie Infettive Istituto Scientifico Giannina Gaslini, Genova L.go G. Gaslini, 5, 16147 Genoa, Italy;(2) U.O.C. Ortopedia e Traumatologia Pediatrica IRCCS Burlo Garofolo, Via dell’Istria, 65, 34137 Trieste, Italy;(3) Servizio di Epidemiologia e Biostatistica Istituto Scientifico Giannina Gaslini, Genova L.go G. Gaslini, 5, 16147 Genoa, Italy;(4) U.O.C. Ortopedia e Traumatologia Pediatrica Istituto Scientifico Giannina Gaslini, Genova Largo G. Gaslini, 5, 16147 Genoa, Italy;
Abstract:The authors carried out a prospective study on 96 patients they treated in Kenya for chronic osteomyelitis from 2000 to 2009. All the patients received orthopedic surgery and antibiotic therapy, when possible based on the antibiotic sensitivity test. Among the 90 patients with at least 12 months’ follow-up, 11 had osteomyelitis relapse (12.2%) and recovery rate was therefore 87.8% with no resulting disability. Risk factors for osteomyelitis relapse were investigated and previous treatment with beta-lactamines, predisposing to onset of methycillin-resistant Staphylococcus aureus (MRSA) infections (P = 0.03, OR = 5.74), and onset of osteomyelitis in the metaepiphyseal region (P < 0.0001) resulted statistically significant. Aim of the study was to evaluate the validity of our treatment of chronic osteomyelitis in Kenya on the basis of outcome.
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