| 复方黄倍软膏抗炎作用的实验研究 |
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| 引用本文： | 郭青云,林清,张建军,李贵堂,宋祖军.复方黄倍软膏抗炎作用的实验研究[J].军医进修学院学报,2011,32(9):968-969. |
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| 作者姓名： | 郭青云 林清 张建军 李贵堂 宋祖军 |
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| 作者单位： | 1. 解放军第309医院,北京,100091
2. 北京中医药大学,北京,100029 |
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| 摘 要： | 目的研究复方黄倍软膏的抗炎作用。方法通过二甲苯致小鼠耳廓肿胀和角叉菜胶致大鼠足趾肿胀模型，观察复方黄倍软膏对炎症的抑制作用。结果复方黄倍软膏能明显抑制二甲苯致小鼠耳廓肿胀度及角叉菜胶致大鼠足趾肿胀度。对照组耳廓肿胀度为（6．348±1．1639）rag，致炎后3h足趾肿胀度（0．423±0．166）ml；复方黄倍软膏组耳廓肿胀度为（2．276±0．766）mg，致炎后3h足趾肿胀度（0．148±0．078）ml，两组比较差异均有统计学意义（P〈0．01）。结论复方黄倍软膏在动物模型中具有很好的抗炎作用。
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| 关 键 词： | 复方黄倍软膏 抗炎药（中药） 模型 动物 |
Anti-inflammatory effect of compound huangbei paste: An experimental study |
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| GUO Qing-yun,LIN Qing,ZHANG Jian-jun,LI Gui-tang,SONG Zu-jun.Anti-inflammatory effect of compound huangbei paste: An experimental study[J].Academic Journal of Pla Postgraduate Medical School,2011,32(9):968-969. |
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| Authors: | GUO Qing-yun LIN Qing ZHANG Jian-jun LI Gui-tang SONG Zu-jun |
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| Institution: | 1Chinese PLA 309 Hospital,Beijing 100091,China;2Beijing University of Traditional Chinese Medicine,Beijing 100029,China |
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| Abstract: | Objective To study the anti-inflammatory effect of compound huangbei paste. Methods A mouse model of ear swelling was induced by dimethylbenzene and a rat model of toe swelling was induced by carrageenin to observe the anti-inflammatory effect of compound huangbei paste. Results Compound huangbei paste could significantly inhibit the dimethylbenzene-induced ear swelling of mice and toe swelling of rats. The ear swelling of mice was （6.348 ± 1.1639）mg and the toe swelling of rats was （0.423 ± 0.166）ml 3h after inflammation in control group. The ear swelling of mice was （2.276 ± 0.766）mg and the toe swelling of rats was （0.148 ± 0.078）ml 3h after inflammation in compound huangbei paste treatment group（P〈0.01）. Conclusion Compound huangbei paste shows strong anti-inflammatory effects in animal models. |
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| Keywords: | Compound Huangbei Paste Anti-Inflammatory Drugs（TCD） Models Animal |
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