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超声引导射频消融治疗小肝癌27例的疗效分析
引用本文:陈宝定,魏金文,薛玉,谢荣,吴新财,邓宏伟,陈德玉. 超声引导射频消融治疗小肝癌27例的疗效分析[J]. 中国医药导报, 2012, 9(34): 62-63,70
作者姓名:陈宝定  魏金文  薛玉  谢荣  吴新财  邓宏伟  陈德玉
作者单位:陈宝定 (江苏大学附属医院超声医学科,江苏镇江,212001); 魏金文 (江苏大学附属医院消化内科,江苏镇江,212001); 薛玉 (江苏大学附属医院超声医学科,江苏镇江,212001); 谢荣 (江苏大学附属医院肿瘤研究院,江苏镇江,212001); 吴新财 (江苏大学附属医院超声医学科,江苏镇江,212001);邓宏伟 (江苏大学附属医院超声医学科,江苏镇江,212001); 陈德玉 (江苏大学附属医院肿瘤研究院,江苏镇江,212001);
基金项目:江苏省镇江市科技支撑-社会发展项目(项目编号:SH2011027);江苏大学临床医学科技发展基金(项目编号:JLY2010155)
摘    要:目的总结分析超声引导下应用Cool-tip射频消融系统治疗小肝癌的疗效。方法回顾性分析2009年3月~2011年10月在我院接受射频消融治疗的小肝癌患者27例,其中原发性小肝癌(sHCC)9例,转移性小肝癌(sMHC)18例,共40枚病灶。随访分析术后肿瘤局部消融效果、术后并发症、围术期肝功能变化、生存率等情况。结果术后1、3个月肿瘤局部完全消融率达95.0%(38/40)、90.0%(36/40);患者术后1、2年总生存率分别为96.3%、88.9%;术后无严重并发症发生,围术期肝功能主要指标14 d内基本恢复。结论对于sHCC和sMHC,射频消融可以取得与手术治疗相当的疗效,并具有并发症少、损伤小的优点。

关 键 词:超声  射频消融  小肝癌  完全消融率  生存率

Efficacy analysis of ultrasound-guilded radiofrequency ablation in treating 27 cases of small hepatic carcinoma
CHEN Baoding,WEI Jinwen,XUE Yu,XIE Rong,WU Xincai,DENG Hongwei,CHEN Deyu. Efficacy analysis of ultrasound-guilded radiofrequency ablation in treating 27 cases of small hepatic carcinoma[J]. China Medical Herald, 2012, 9(34): 62-63,70
Authors:CHEN Baoding  WEI Jinwen  XUE Yu  XIE Rong  WU Xincai  DENG Hongwei  CHEN Deyu
Affiliation:1.Department of Ultrasound Medicine,the Affiliated Hospital of Jiangsu University,Jiangsu Province,Zhenjiang 2120012,China;2.Department of Gastroenterology,the Affiliated Hospital of Jiangsu University,Jiangsu Province,Zhenjiang 2120012,China;3.Tumor Research Institute,the Affiliated Hospital of Jiangsu University,Jiangsu Province,Zhenjiang 212001,China
Abstract:Objective To summarize and analyze efficacy of ultrasound-guilded treatment for small hepatic carcinoma with Cool-tip radiofrequency ablation(RFA) system.Methods 27 cases of small hepatic carcinoma treated by radiofrequency ablation in our hospital from March 2009 to October 2011 were analyzed retrospectively with 9 cases of small hepatocellu lar carcinoma(sHCC),8 cases of small metastatic hepatic carcinoma(sMHC) and a total of 40 lesions.Postoperative local tumor ablation effect,postoperative complications,perioperative changes in liver function and survival rate were followedup and analyzed.Results Local tumor complete ablation effect rates 1,3 months after treatment were 95.0%(38/40) and 90.0%(36/40);overall survival rates 1,2 years after treatment were 96.3% and 88.9%;no severe postoperative com plication was found,perioperative liver function was basically resumed in 14 days.Conclusion RFA can achieve the equivalent efficacy as the surgical treatment for sHCC and sMHC with fewer complications and damage.
Keywords:Ultrasound  Radiofrequency ablation  Small hepatic carcinoma  Complete ablation rate  Survival rate
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