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0-1岁婴儿出生缺陷的流行病学调查
引用本文:倪少义,陈少娜,吴翔,蔡幸生,黄伟鹏,王榕生,洪艳苹,倪少英,卢晓航,何洁壁. 0-1岁婴儿出生缺陷的流行病学调查[J]. 中国医药导报, 2012, 9(35): 137-139
作者姓名:倪少义  陈少娜  吴翔  蔡幸生  黄伟鹏  王榕生  洪艳苹  倪少英  卢晓航  何洁壁
作者单位:倪少义 (广东省揭阳市揭东县计划生育服务站,广东揭东,515500);陈少娜 (广东省荣誉军人康复医院,广东广州,510260); 吴翔 (广东省揭阳市揭东县计划生育服务站,广东揭东,515500); 蔡幸生 (广东省揭阳市人民医院,广东揭阳,522000); 黄伟鹏 (广东省揭阳市人民医院,广东揭阳,522000); 王榕生 (广东省揭阳市人民医院,广东揭阳,522000); 洪艳苹 (广东省揭阳市疾病预防控制中心,广东揭阳,522000);倪少英 (广东省东莞市东城医院,广东东莞,523007); 卢晓航 (广东省揭阳市人民医院,广东揭阳,522000); 何洁壁 (广东省揭阳市揭东县计划生育服务站,广东揭东,515500);
基金项目:广东省人口和计划生育委员会科研项目(项目编号:20110249)
摘    要:目的了解揭阳部分地区0-1岁婴儿出生缺陷的发病情况,确定预防的重点人群,为出生缺陷的预防和孕前、孕期保健提供依据。方法采用普查的方式,对揭东县、普宁市、榕城区三地2011年3月3日-2012年5月2日出生的婴儿进行调查。出生缺陷以临床诊断为依据,病种及统计标准参照国际出生缺陷监测情报交换所的规定。结果共监测10 773名婴儿,发现出生缺陷238例;婴儿出生缺陷排名前5位的疾病分别是先天性心脏病、马蹄内翻足、多指(趾)、唇(腭)裂和胎儿水肿综合征;男婴、低体重出生婴儿、孕母未服用叶酸、维生素、微量元素的婴儿以及家庭成员有吸烟、酗酒的婴儿,出生缺陷发生率相对较高(P〈0.05)。结论揭阳市部分地区0-1岁婴儿出生缺陷发生率为220.92/万,略高于全国平均水平,需要引起各方重视。加强宣传教育,做好出生缺陷的孕、产前筛查与预防工作迫在眉睫。

关 键 词:0-1岁  出生缺陷  发生率  流行病学  计划生育

Epidemiological survey on 0-1 years old baby with birth defect
NI Shaoyi,CHEN Shaona,WU Xiang,CAI Xingsheng,HUANG Weipeng,WANG Rongsheng,HONG Yanping,NI Shaoying,LU Xiaohang,HE Jiebi. Epidemiological survey on 0-1 years old baby with birth defect[J]. China Medical Herald, 2012, 9(35): 137-139
Authors:NI Shaoyi  CHEN Shaona  WU Xiang  CAI Xingsheng  HUANG Weipeng  WANG Rongsheng  HONG Yanping  NI Shaoying  LU Xiaohang  HE Jiebi
Affiliation:1.Family-planning Service Outlet of Jiedong County in Jieyang City,Guangdong Province,Jiedong 515500,China;2.Guangdong Rehabilitation Hospitals for Glory Soldiers,Guangdong Province,Guangzhou 510260,China;3.The People’s Hospital of Jieyang City,Guangdong Province,Jieyang 522000,China;4.Centers for Disease Control and Prevention of Jieyang City,Guangdong Province,Jieyang 522000,China;5.Dongcheng Hospital of Dongguan City,Guangdong Province,Dongguan 523007,China
Abstract:Objective To understand the incidence of birth defect in 0-1 years old baby in some regions of Jieyang,then to determine the focus groups for prevention.So that it can provide a foundation for birth defect prevention,pre-pregnancy and pregnancy care.Methods Those babies,who were born in Jiedong County,Puning City and Rongcheng District from March 3,2011 to May 2,2012 were surveyed by general investigation.Birth defect based on clinical diagnosis,its entity and statistical standard referred to the regulations of International Centre on Birth Defects and Prematurity.Results 238 cases of birth defect babies were found out of 10 773 cases of monitored new babies.The top five diseases of baby birth defects were congenital heart disease,talipes equinovarus,polydactyly,cleft lip and palate and fetal-edematous-syndrome.Some babies had higher incidence of birth defects,such as baby boy,low birth weight baby,and those babies whose mother did not take folic acid,vitamin and trace elements during pregnancy and whose family members smoking and excessive drinking(P 0.05).Conclusion The incidence rate of birth defects in 0-1 years old baby is 220.92 per ten thousand in some regions of Jieyang City.It is slightly higher than the national average,so it needs attention from each side.Strengthening propaganda and education,screening and preventing birth defects are matters of great urgency.
Keywords:0-1 years old  Birth defect  Incidence rate  Epidemiology  Family planning
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