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缬沙坦对老年高血压患者睡眠质量的影响
作者姓名:李兵  孙成磊  程国良  任磊
作者单位:国家手性制药工程技术研究中心;安徽省阜阳市人民医院
摘    要:目的探讨缬沙坦对老年高血压患者睡眠质量的影响。方法选取本院2018年6月至2019年12月收治的老年高血压患者84例,随机分为观察组和对照组,每组42例。两组患者均采用护理干预,观察组在此基础上口服缬沙坦分散片,每次80mg,每日1次,连续治疗2周。利用匹兹堡睡眠质量指数对睡眠质量进行评价,记录入睡潜伏期、觉醒次数、睡眠时间。结果两组治疗1周及2周后与治疗前对比具有统计学差异(P<0.05),治疗1周及2周后两组对比具有统计学差异(P<0.05)。观察组患者需要(34.7±4.5)分钟入睡,且持续睡眠时间是(5.9±1.1)小时;对照组需要(44.8±5.4)分钟入睡,且持续睡眠时间是(4.4±0.9)小时,两组患者睡眠参数对比差异具有统计学意义(P<0.05)。结论降压药物缬沙坦能够有效改善老年高血压患者睡眠障碍,延长睡眠时间,降低觉醒次数,对提高睡眠质量具有积极作用。

关 键 词:缬沙坦  老年高血压  睡眠障碍

Effects of valsartan on sleep quality in elderly patients with hypertension
Authors:LI Bing  SUN Chenglei  CHENG Guoliang  REN Lei
Institution:(National Center for chiral pharmaceutical engineering and technology, Linyi 276000;Anhui Fuyang people's hospital, Fuyang 236000, China.)
Abstract:Objective To investigate the effect of valsartan on sleep quality in elderly patients with hypertension.Methods 84 elderly hypertensive patients admitted to our hospital from June 2018 to December 2019 were randomly divided into observation group and control group,with 42 cases in each group.The two groups of patients all adopted nursing intervention to nursing elderly patients with hypertension,and the observation group took valsartan capsules orally,80mg once a day,on this basis for two weeks.Pittsburgh sleep quality index was used to evaluate sleep quality,and sleep latency,number of awakenings and sleep duration were recorded.Results There were statistically significant differences between the two groups after 1 and 2 weeks of treatment and before treatment(P<0.05),and there were statistically significant differences between the two groups after 1 week of treatment and 2 days after treatment(P<0.05).Patients in the observation group needed(34.7±4.5)min to fall asleep,and the duration of sleep was(5.9±1.1)h.The control group needed(44.8±5.4)min to fall asleep,and the duration of sleep was(4.4±0.9)h.The difference of sleep parameters between the two groups was statistically significant(P<0.05).Conclusion The antihypertensive drug valsartan can effectively improve sleep disorders in elderly patients with hypertension,prolong sleep time,reduce the number of awakenations,and have a positive effect on improving sleep quality.
Keywords:valsartan  Senile hypertension  somnipathy
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