网织红细胞参数在儿童血液病中的应用

目的:探讨网织红细胞参数在儿童血液病中的临床应用价值.方法:应用Sysmex XE-2100全自动血细胞分析仪检测106例儿童血液病患儿的网织红细胞计数(RET#)、网织红细胞百分比(RET)、未成熟网织红细胞比率(IRF)、低荧光强度网织红细胞比值(LFR)、中荧光强度网织红细胞比值(MFR)、高荧光强度网织红细胞比值(HFR)等参数.结果:营养性缺铁性贫血、溶血性贫血、血小板减少性紫癜患儿RET、IRF等指标显著增高(P＜0.05),再生障碍性贫血、白血病患儿RET#显著降低(P＜0.05),IRF显著增高(P＜0.05).结论:测定网织红细胞及其相关参数有助于判断骨髓生成红细胞的活动度,对贫血类型的鉴别诊断有实用价值.

Application of reticulocyte parameters in children''''s blood diseases

Objective To study the clinical value of reticulocyte parameters in children's blood diseases detected by Sysmex XE-2100 automatic blood analysor. Methods Reticulocyte absolute value(RET#),reticulocyte percentage(RET), immature reticulocyte formation(IRF),low scattered light intensity reticulocyte percentage(LFR),middle scattered light intensity reticulocyte percentage(MFR) and high scattered light intensity reticulocyte percentage(HLR) of 106 cases in-patients' blood sample were detected by Sysmex XE-2100 automatic blood analysor. Results In the groups of IDA,HA and ITP,RET# and IRF were notably higher than those of control group(P<0.05). In the groups of AA and leukemia, RET# were notably lower than those of the control group(P<0.05), but IRF was notably higher than that of the control group(P<0.05).Conclusion The detection of reticulocyte and its parameters will help decide the activity of red blood cell,and it has important practical value in diagnosis of anemia type.